SCHEMBL3301451

SCHEMBL3301451

CCCCCCCCNc1nc(N)nc(N)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
TLR8 Q9NR97 10/20 0.51
DNM2 P50570 3/20 0.49
KCNH3 Q9ULD8 2/20 0.49
TLR7 Q9NYK1 4/20 0.47
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
HSP90AA1 P07900 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
CASP3 P42574 1/20 0.46
HTT P42858 1/20 0.46
CDK9 P50750 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754956 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL3300077 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL3296575 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL1034958 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL3301367 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL468517 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL8752650 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL4451532 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL3297429 1.00 KMT2A (0.53) KMT2ATLR8DNM2KCNH3TLR7
SCHEMBL2851069 0.98 TLR8 (0.53) KMT2ATLR8DNM2KCNH3TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250070210-A1 ELECTROLYTE NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2025-02-27 US disclosed
EP-4443571-A1 ELECTROLYTE National Institute Of Advanced Industrial Science and Technology (JP) 2024-10-09 EP disclosed
WO-2023120421-A1 ELECTROLYTE 国立研究開発法人産業技術総合研究所 2023-06-29 WO disclosed
WO-2023120421-A1 ELECTROLYTE 国立研究開発法人産業技術総合研究所 2023-06-29 WO disclosed
CN-106574099-B Hydrophilic material comprising sulfonic acid based copolymer and amino resins 三井化学株式会社 2019-06-21 CN disclosed
US-7741390-B2 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2010-06-22 US disclosed
US-20090131564-A1 COORDINATION-POLYMERIC TRIETHANOLAMINEPERCHLORATO(TRIFLATO)METAL INNER COMPLEXES AS ADDITIVES FOR SYNTHETIC POLYMERS IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) 2009-05-21 US disclosed
US-20090105387-A1 Coordination-polymeric triethanolamineperchlorato(triflato)metal inner complexes as additives for synthetic polymers ARTEMIS RESEARCH GMBH & CO. KG (DE) 2009-04-23 US disclosed
EP-0945446-A1 CYANOETHYLMELAMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250070210-A1 ELECTROLYTE MEN1, MON2, PMS2 KMT2A 186/4885TLR8 4054/4885DNM2 1229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.