Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330168 | 1.00 | LMNA (0.49) | LMNATDP1TSHRTK1MAPK1 | |
| SCHEMBL18204470 | 0.98 | LMNA (0.50) | LMNATDP1TSHRTK1MAPK1 | |
| SCHEMBL15978100 | 0.98 | LMNA (0.50) | LMNATDP1TSHRTK1MAPK1 | |
| SCHEMBL2434556 | 0.86 | LMNA (0.55) | LMNATDP1TSHRTK1MAPK1 | |
| SCHEMBL15450091 | 0.86 | LMNA (0.55) | LMNATDP1TSHRTK1MAPK1 | |
| SCHEMBL15869135 | 0.86 | LMNA (0.55) | LMNATDP1TSHRTK1MAPK1 | |
| SCHEMBL7867427 | 0.84 | ESR1 (0.54) | LMNATDP1TSHRMAPK1SLC6A2 | |
| SCHEMBL19810157 | 0.83 | LMNA (0.56) | LMNATDP1TSHRMAPK1HIF1A | |
| SCHEMBL19810156 | 0.83 | LMNA (0.56) | LMNATDP1TSHRMAPK1HIF1A | |
| SCHEMBL19810158 | 0.83 | LMNA (0.56) | LMNATDP1TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041459-B1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI SPA (IT) | 2019-04-03 | — | — | EP | claimed |
| EP-2593097-B1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI SPA (IT) | 2016-08-24 | — | — | EP | claimed |
| EP-3041459-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | Giuliani S.p.A. (IT) | 2016-07-13 | — | — | EP | claimed |
| WO-2015033276-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2015-03-12 | — | — | WO | claimed |
| EP-2593097-A1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | Giuliani S.p.A. (IT) | 2013-05-22 | — | — | EP | claimed |
| US-20130108564-A1 | Compounds with a Skin Pigmenting Activity And Pharmaceutical or Cosmetic Compositions Containing Them | GIULIANI S.P.A. (IT) | 2013-05-02 | — | — | US | claimed |
| WO-2012007572-A1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2012-01-19 | — | — | WO | claimed |
| EP-2407163-A1 | Compounds with a skin pigmenting activity and pharmaceutical or cosmetic compositions containing them | Giuliani S.p.A. (IT) | 2012-01-18 | — | — | EP | claimed |
| EP-3041459-B1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI SPA (IT) | 2019-04-03 | — | — | EP | disclosed |
| EP-2593097-B1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI SPA (IT) | 2016-08-24 | — | — | EP | disclosed |
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2016-07-28 | — | — | US | disclosed |
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2016-07-28 | — | — | US | disclosed |
| US-9192595-B2 | Compounds with a skin pigmenting activity and pharmaceutical or cosmetic compositions containing them | GIULIANI S.P.A. (IT) | 2015-11-24 | — | — | US | disclosed |
| US-9192595-B2 | Compounds with a skin pigmenting activity and pharmaceutical or cosmetic compositions containing them | GIULIANI S.P.A. (IT) | 2015-11-24 | — | — | US | disclosed |
| WO-2015033276-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | GIULIANI S.P.A. (IT) | 2015-03-12 | — | — | WO | disclosed |
| US-20130108564-A1 | Compounds with a Skin Pigmenting Activity And Pharmaceutical or Cosmetic Compositions Containing Them | GIULIANI S.P.A. (IT) | 2013-05-02 | — | — | US | disclosed |
| US-20130108564-A1 | Compounds with a Skin Pigmenting Activity And Pharmaceutical or Cosmetic Compositions Containing Them | GIULIANI S.P.A. (IT) | 2013-05-02 | — | — | US | disclosed |
| WO-2012007572-A1 | COMPOUNDS WITH A SKIN PIGMENTING ACTIVITY AND PHARMACEUTICAL OR COSMETIC COMPOSITIONS CONTAINING THEM | GIULIANI S.P.A. (IT) | 2012-01-19 | — | — | WO | disclosed |
| EP-2407163-A1 | Compounds with a skin pigmenting activity and pharmaceutical or cosmetic compositions containing them | Giuliani S.p.A. (IT) | 2012-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160213635-A1 | COMPOSITIONS USEFUL IN THE PREVENTION OR TREATMENT OF SKIN CANCER | PKLR, AKR1C3, HK1 | LMNA 105/4885TDP1 1985/4885TSHR 3804/4885 |
| US-20130108564-A1 | Compounds with a Skin Pigmenting Activity And Pharmaceutical or Cosmetic Compositions Containing Them | TYR, MC1R, HK1 | LMNA 1303/4885TDP1 4174/4885TSHR 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.