SCHEMBL3301691

SCHEMBL3301691

CCN(CC)c1cccc([SiH](O[SiH](c2cccc(N(CC)CC)c2)c2cccc(N(CC)CC)c2)c2cccc(N(CC)CC)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
CYP3A4 P08684 2/20 0.52
TERT O14746 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.39
KDM4E B2RXH2 4/20 0.39
THRB P10828 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
GAA P10253 2/20 0.39
RECQL P46063 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39
S100B P04271 1/20 0.38
MAPT P10636 5/20 0.37
MAPK1 P28482 4/20 0.37
HTT P42858 1/20 0.37
TSHR P16473 2/20 0.36
KMT2A Q03164 5/20 0.35
GFER P55789 2/20 0.35
PSMD14 O00487 1/20 0.35
MEN1 O00255 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293275 0.83 ALDH1A1 (0.37) ALDH1A1CYP3A4KDM4EGAAMAPT
SCHEMBL3293296 0.79 ALDH1A1 (0.47) ALDH1A1TERTL3MBTL1KDM4EHSD17B10
SCHEMBL1574035 0.77 ALDH1A1 (0.71) ALDH1A1CYP3A4TERTL3MBTL1KDM4E
SCHEMBL3298751 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4TERTL3MBTL1KDM4E
SCHEMBL3296167 0.71 TP53 (0.41) ALDH1A1L3MBTL1KDM4EMAPTMAPK1
SCHEMBL14283564 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4TERTL3MBTL1KDM4E
SCHEMBL457496 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4TERTL3MBTL1KDM4E
SCHEMBL30565135 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4TERTL3MBTL1KDM4E
SCHEMBL3425607 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4TERTL3MBTL1KDM4E
SCHEMBL30565134 0.70 ALDH1A1 (0.61) ALDH1A1CYP3A4TERTL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 ALDH1A1 1865/4885CYP3A4 1577/4885TERT 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.