Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3301691 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBGAACYP3A4 | |
| SCHEMBL8664260 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBGAACYP3A4 | |
| SCHEMBL3299032 | 0.80 | EGFR (0.40) | ALDH1A1KDM4EPOLBGAASLC16A3 | |
| SCHEMBL11000207 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBGAACYP3A4 | |
| SCHEMBL10689574 | 0.74 | HDAC6 (0.45) | ALDH1A1KDM4EPOLBGAACYP3A4 | |
| SCHEMBL5284253 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBGAACYP3A4 | |
| SCHEMBL8664850 | 0.73 | MTNR1A (0.58) | SLC16A3SLC16A1MTNR1AMTNR1B | |
| SCHEMBL3293296 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBMAPT | |
| Lithium Ion SCHEMBL19732786 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBGAACYP3A4 | |
| SCHEMBL11133767 | 0.73 | MAPT (0.65) | ALDH1A1KDM4EPOLBGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741393-B2 | Organic silicon-based compound and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | ARSA, OR10J3, HDAC10 | ALDH1A1 1865/4885KDM4E 1578/4885POLB 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.