Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | IDO1 | P14902 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337201 | 0.93 | PNMT (0.60) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL11520705 | 0.91 | PNMT (0.58) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL11828147 | 0.87 | PNMT (0.60) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL26849008 | 0.87 | PNMT (0.54) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL27396074 | 0.85 | PNMT (0.57) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL16933811 | 0.85 | PNMT (0.52) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL3301733 | 0.84 | PNMT (0.56) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL10965769 | 0.83 | CYP1A2 (0.54) | PNMTTAAR1IDO1ALDH1A1CYP1A2 | |
| SCHEMBL283449 | 0.81 | PNMT (0.65) | PNMTTAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL42705 | 0.81 | PNMT (1.00) | PNMTTAAR1IDO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| WO-2020131678-A1 | CLEANSING COMPOSITION AND METHOD | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2017063848-A1 | SANITISING AND DISINFECTING COMPOSITIONS | UNILEVER N.V. (NL) | 2017-04-20 | — | — | WO | disclosed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| US-8299072-B2 | Pyrazolylmethylamine compounds as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-30 | — | — | US | disclosed |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-04-15 | — | — | US | disclosed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | disclosed |
| EP-0817607-A1 | LIQUID CLEANSING FORMULATIONS | UNILEVER PLC (GB) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996029049-A1 | LIQUID CLEANSING FORMULATIONS | UNILEVER PLC (GB) | 1996-09-26 | — | — | WO | disclosed |
| EP-0428081-B1 | Method for producing diarylmethanes | KUREHA CHEMICAL IND CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5296601-A | Reaction of aromatic chloride with carbon monoxide and alcohol | NIHON NOHYAKU CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0282266-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID AMIDES OR ESTERS | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5142057-A | Reacting an organic chloride with carbon monoxide and amine | NIHON NOHYAKU CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5073176-A | Permselective | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-5068481-A | Reaction of benzyl chloride with benzene or alkylbenzene in the presence of a zeolite catalyst | KUREHA KAGAKU KOGYO K.K. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0428081-A1 | Method for producing diarylmethanes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-22 | — | — | EP | disclosed |
| EP-0282266-A2 | Process for producing carboxylic acid amides or esters | NIHON NOHYAKU CO., LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
| US-4434246-A | Process for preparing ethylene glycol and lower monohydric alcohols from syngas using a novel catalyst system | TEXACO INC. (US) | 1984-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | PNMT 2489/4885TAAR1 3270/4885IDO1 2957/4885 |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1I, CACNA1C, ORAI1 | PNMT 309/4885TAAR1 2273/4885IDO1 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.