Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11828147 | 0.91 | PNMT (0.60) | PNMTTAAR1IDO1MEN1CYP3A4 | |
| SCHEMBL11403614 | 0.89 | CALM1 (0.52) | NR1H2CALM1HTR2AMEN1CYP3A4 | |
| SCHEMBL4423210 | 0.84 | SIGMAR1 (0.53) | PNMTTAAR1IDO1CALM1HTR2A | |
| SCHEMBL3302008 | 0.84 | PNMT (0.68) | PNMTTAAR1IDO1MEN1CYP3A4 | |
| SCHEMBL2861971 | 0.83 | CTRC (0.47) | NR1H2CALM1HTR2AP2RX7MEN1 | |
| SCHEMBL6337201 | 0.82 | PNMT (0.60) | PNMTTAAR1IDO1CYP3A4KDM4E | |
| SCHEMBL27610685 | 0.82 | PNMT (0.50) | PNMTTAAR1IDO1P2RX7MEN1 | |
| SCHEMBL1042000 | 0.82 | PNMT (0.55) | PNMTTAAR1IDO1CYP3A4KDM4E | |
| SCHEMBL11030386 | 0.81 | NR1H2 (0.45) | NR1H2CALM1HTR2AMEN1CYP3A4 | |
| SCHEMBL26135124 | 0.81 | TAAR1 (0.59) | PNMTTAAR1IDO1NR1H2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104716352-A | Use of crosslinking type polybenzimidazole porous separating membrane in liquid flow battery | DALIAN CHEMICAL PHYSICS INST | 2015-06-17 | — | — | CN | claimed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| CN-103055723-A | Cross-linking type polybenzimidazole porous separation membrane and preparation method and application thereof | UNIV LIAONING NORMAL | 2013-04-24 | — | — | CN | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| US-9388282-B2 | Method of thiophenol removal from poly(arylene sulfide) polymer compositions | SOLVAY SPECIALTY POLYMERS USA, LLC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20160168357-A1 | Poly(Arylene Sulfide) Compositions and Processes of Producing Same | SOLVAY SA (BE) | 2016-06-16 | — | — | US | disclosed |
| US-20160145393-A1 | PROCESS FOR PRODUCTION OF POLY(ARYLENE SULFIDE) | SOLVAY SA (BE) | 2016-05-26 | — | — | US | disclosed |
| WO-2016079243-A1 | A PROCESS FOR PRODUCTION OF POLY(ARYLENE SULFIDE) | SOLVAY SA (BE) | 2016-05-26 | — | — | WO | disclosed |
| US-20160130400-A1 | CONTINUOUS PROCESS FOR PRODUCING POLY(ARYLENE SULFIDE) | SOLVAY SA (BE) | 2016-05-12 | — | — | US | disclosed |
| WO-2016071341-A1 | A CONTINUOUS PROCESS FOR PRODUCING POLY(ARYLENE SULFIDE) | SOLVAY SA (BE) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016038218-A1 | A PROCESS FOR PREVENTING THIOPHENOL FORMATION AND/OR ACCUMULATION DURING PRODUCTION OF POLY(ARYLENE SULFIDE) | SOLVAY SA (BE) | 2016-03-17 | — | — | WO | disclosed |
| US-20160075832-A1 | Process for Preventing Thiophenol Formation and/or Accumulation During Production of Poly(Arylene Sulfide) | SOLVAY SA (BE) | 2016-03-17 | — | — | US | disclosed |
| US-20150105524-A1 | Method of Improving the Melt Properties of Poly(Arylene Sulfide) Polymers | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-04-16 | — | — | US | disclosed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | disclosed |
| CN-103055723-A | Cross-linking type polybenzimidazole porous separation membrane and preparation method and application thereof | UNIV LIAONING NORMAL | 2013-04-24 | — | — | CN | disclosed |
| US-8299072-B2 | Pyrazolylmethylamine compounds as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-30 | — | — | US | disclosed |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-04-15 | — | — | US | disclosed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | disclosed |
| US-5015710-A | Catalytic addition polymerization | HERCULES INCORPORATED (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0423521-A1 | Process for producing polymer molded article | HERCULES INCORPORATED (US) | 1991-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | PNMT 2489/4885TAAR1 3270/4885IDO1 2957/4885 |
| US-20100094006-A1 | NOVEL PYRAZOLYLMETHYLAMINE COMPOUNDS AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1I, CACNA1C, ORAI1 | PNMT 309/4885TAAR1 2273/4885IDO1 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.