Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13393378 | 0.89 | KDM1A (0.52) | KDM1AHTR1ASMN1; SMN2 | |
| SCHEMBL13393376 | 0.89 | KDM1A (0.52) | KDM1AHTR1ADRD2SLC6A4ADRA1A | |
| SCHEMBL13393373 | 0.89 | KDM1A (0.52) | KDM1AHTR1ACHRM2ADRA2ACHRM1 | |
| SCHEMBL3302413 | 0.89 | KDM1A (0.62) | KDM1AHTR1ACHRM2ADRA2ACHRM1 | |
| SCHEMBL13393419 | 0.81 | KDM1A (0.63) | KDM1ACHRNA7 | |
| SCHEMBL13393386 | 0.79 | KDM1A (0.65) | KDM1ACHRNA7HTR1ACHRM2CHRM1 | |
| SCHEMBL13393389 | 0.79 | DRD2 (0.58) | KDM1AHTR1ACHRM2ADRA2ACHRM1 | |
| SCHEMBL13393392 | 0.79 | KDM1A (0.51) | KDM1AHTR1ACHRM2ADRA2ACHRM1 | |
| SCHEMBL13393395 | 0.79 | KDM1A (0.51) | KDM1AHTR1ACHRM2ADRA2ACHRM1 | |
| SCHEMBL2287889 | 0.77 | GAA (0.48) | CACNA1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099871-A1 | ANTI-PSYCHOTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLER DWIGHT W | 2010-04-22 | — | — | US | disclosed |
| US-20100099871-A1 | ANTI-PSYCHOTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLER DWIGHT W | 2010-04-22 | — | — | US | disclosed |
| US-20100099871-A1 | ANTI-PSYCHOTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | MILLER DWIGHT W | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099871-A1 | ANTI-PSYCHOTIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | HTR2A, HTR2C, HTR5A | KDM1A 3546/4885CHRNA7 177/4885HTR1A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.