Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.64 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071971 | 0.91 | ALDH1A3 (0.59) | DHODHALDH1A3HSD17B10TP53MAPT | |
| SCHEMBL2315115 | 0.87 | ALDH1A3 (0.55) | DHODHALDH1A3HSD17B10TP53MAPT | |
| SCHEMBL1420203 | 0.85 | DHODH (0.60) | DHODHALDH1A3HSD17B10TP53MAPT | |
| SCHEMBL19660462 | 0.82 | ALDH1A3 (0.67) | ALDH1A3HSD17B10TP53MAPTGAA | |
| SCHEMBL5251711 | 0.81 | ALDH1A3 (0.60) | ALDH1A3TP53MAPTGAAPOLB | |
| SCHEMBL1481133 | 0.81 | DHODH (0.94) | DHODHALDH1A3HSD17B10TP53GAA | |
| SCHEMBL5737921 | 0.81 | ALDH1A3 (0.72) | ALDH1A3HSD17B10TP53MAPTLMNA | |
| SCHEMBL2315617 | 0.81 | ALDH1A3 (0.65) | ALDH1A3HSD17B10TP53MAPTLMNA | |
| SCHEMBL2318180 | 0.81 | ALDH1A3 (0.61) | ALDH1A3HSD17B10TP53MAPTLMNA | |
| SCHEMBL21237193 | 0.79 | ALDH1A3 (0.63) | ALDH1A3HSD17B10TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404707-B2 | Imidazo [1, 2-a] pyrrolo [3, 2-c] pyridine compounds useful as pestivirus inhibitors | UNIVERSITE D'AUVERGNE CLERMONT 1 (FR) | 2013-03-26 | — | — | US | disclosed |
| US-20100093781-A1 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | UNIVERSITE D'AUVERGNE CLERMONT 1 (FR) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093781-A1 | IMIDAZO [1, 2-A] PYRROLO [3, 2-C] PYRIDINE COMPOUNDS USEFUL AS PESTIVIRUS INHIBITORS | PPM1D, CDKN1A, PPM1A | DHODH 497/4885ALDH1A3 3587/4885HSD17B10 4067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.