⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15465485 | 0.81 | FDPS (0.37) | — | |
| SCHEMBL3067280 | 0.80 | FDPS (0.41) | — | |
| SCHEMBL1094446 | 0.79 | — | — | |
| SCHEMBL3320765 | 0.77 | — | — | |
| SCHEMBL25581260 | 0.76 | FDPS (0.39) | — | |
| SCHEMBL13820040 | 0.76 | FDPS (0.35) | — | |
| SCHEMBL12811510 | 0.74 | FDPS (0.38) | — | |
| SCHEMBL10680 | 0.74 | — | — | |
| SCHEMBL23873075 | 0.73 | — | — | |
| SCHEMBL19978777 | 0.73 | FDPS (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659745-A1 | Substituted 1-aryl pyrazoles | BAYER AG (DE) | 1995-06-28 | — | — | EP | claimed |
| US-12091399-B2 | Phenyltetrazole derivatives as plasma kallikrein inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-09-17 | — | — | US | disclosed |
| CN-117136052-A | CDK inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-11-28 | — | — | CN | disclosed |
| US-20230000773-A1 | NOVEL HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ARES CAPITAL CORPORATION, AS AGENT | 2023-01-05 | — | — | US | disclosed |
| CN-115093408-A | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2022-09-23 | — | — | CN | disclosed |
| EP-3412663-B1 | NITROGEN-CONTAINING HETEROCYCLE AND CARBOCYCLE DERIVATIVES HAVING TRKA INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2022-09-07 | — | — | EP | disclosed |
| EP-4031527-A1 | HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | ModernaTX, Inc. (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114746398-A | Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents | 摩登纳特斯有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114401965-A | Benzylamine-containing 5, 6-heteroaromatic compounds useful against mycobacterial infections | 盐野义制药株式会社 | 2022-04-26 | — | — | CN | disclosed |
| EP-3330256-B1 | HETEROCYCLIC DERIVATIVE HAVING TrkA-INHIBITING ACTIVITY | SHIONOGI & CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-1293501-B1 | Substituted 1-aryl-pyrazoles and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-0659745-B1 | Substituted 1-aryl pyrazoles | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-1293501-A1 | Substituted 1-aryl-pyrazoles and their use as pesticides | Bayer CropScience AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-RE37495-E1 | Substituted 1-arylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| US-5580843-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| EP-0659745-A1 | Substituted 1-aryl pyrazoles | BAYER AG (DE) | 1995-06-28 | — | — | EP | disclosed |
| US-4973600-A | CONGESTIVE HEART FAILURE, GOUT, DIRUETICS, HYPERURICEMIA | TANABE SEIYAKU CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4965282-A | DIURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| CN-1035828-A | Benzo benzodioxole derivatives and preparation method thereof | TANABE SEIYAKU CO (JP) | 1989-09-27 | — | — | CN | disclosed |
| EP-0329326-A1 | Benzodioxole derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |