⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067280 | 0.88 | FDPS (0.41) | — | |
| Ether SCHEMBL6717167 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL23873075 | 0.80 | — | — | |
| SCHEMBL15465485 | 0.79 | FDPS (0.37) | — | |
| SCHEMBL3303667 | 0.79 | — | — | |
| SCHEMBL14722200 | 0.78 | THRB (0.39) | — | |
| SCHEMBL11617 | 0.78 | FDPS (0.33) | — | |
| SCHEMBL22451154 | 0.78 | FDPS (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL27898568 | 0.77 | FDPS (0.32) | — | |
| SCHEMBL19719187 | 0.77 | CA12 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385938-B1 | SULFONAMIDE DERIVATIVES | PFIZER LTD (GB) | 2015-03-04 | — | — | EP | disclosed |
| EP-2385938-B1 | SULFONAMIDE DERIVATIVES | PFIZER LTD (GB) | 2015-03-04 | — | — | EP | disclosed |
| CN-102348697-B | Sulfonamide derivatives | PFIZER LTD | 2014-12-10 | — | — | CN | disclosed |
| US-8907101-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2014-12-09 | — | — | US | disclosed |
| US-8907101-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2014-12-09 | — | — | US | disclosed |
| US-8907101-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2014-12-09 | — | — | US | disclosed |
| US-20130338111-A1 | Sulfonamide Derivatives | ICAGEN, INC. (US) | 2013-12-19 | — | — | US | disclosed |
| US-8541588-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2013-09-24 | — | — | US | disclosed |
| US-8541588-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2013-09-24 | — | — | US | disclosed |
| US-8541588-B2 | Sulfonamide derivatives | PFIZER LIMITED (GB) | 2013-09-24 | — | — | US | disclosed |
| EP-1157002-A1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | Pfizer Limited (GB) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000051972-A1 | 1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |
| WO-1997001552-A1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-01-16 | — | — | WO | disclosed |
| EP-0491218-A1 | Benzodiazepinones | F. HOFFMANN-LA ROCHE AG (CH) | 1992-06-24 | — | — | EP | disclosed |
| EP-0268800-B1 | PHENOXYACETIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4973600-A | CONGESTIVE HEART FAILURE, GOUT, DIRUETICS, HYPERURICEMIA | TANABE SEIYAKU CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4965282-A | DIURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0329326-A1 | Benzodioxole derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-23 | — | — | EP | disclosed |
| US-4853404-A | DIURETIS, SALURETICS, URICOSURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0268800-A1 | Phenoxyacetic acid derivatives and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-01 | — | — | EP | disclosed |