SCHEMBL3303874

SCHEMBL3303874

O=[C]C(O)(CO)P(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
FDPS P14324 3/20 0.32
PDE3A Q14432 2/20 0.32
ADRB3 P13945 1/20 0.32
PDE4D Q08499 1/20 0.32
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8831995 0.67
SCHEMBL2702334 0.65 FDPS (0.50) LMNAFDPSPDE3AADRB3PDE4D
Phosphoric Acid SCHEMBL28897780 0.64 LMNA (0.37) LMNAFDPSPDE3AADRB3PDE4D
SCHEMBL28195818 0.61 LMNA (0.35) LMNAFDPSPDE3AADRB3PDE4D
SCHEMBL11139313 0.61
Phosphoric Acid SCHEMBL25335734 0.58
SCHEMBL19668697 0.57 LMNA (0.45) LMNAFDPSPGK1PGK2
SCHEMBL15411105 0.57 FDPS (0.48) LMNAFDPSPDE3AADRB3PDE4D
SCHEMBL6667332 0.57 FDPS (0.48) LMNAFDPSPDE3AADRB3PDE4D
SCHEMBL7401246 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737816-A1 INTEGRIN MODULATORS AND METHODS FOR THEIR USE Billings Pharmaceuticals, Inc. (US) 2007-01-03 EP claimed
WO-2005087717-A1 INTEGRIN MODULATORS AND METHODS FOR THEIR USE BILLINGS PHARMACEUTICALS INC. (US) 2005-09-22 WO claimed
EP-1003558-B1 LIPID-POLYAMIDE CONJUGATES AND COMPOSITIONS FOR NUCLEIC ACID DELIVERY CHIRON CORP (US) 2004-03-17 EP claimed
US-6572881-B1 Delivery of polynucleotides to cells; polylactam CHIRON CORPORATION 2003-06-03 US claimed
US-6569450-B1 For facilitating the delivery of polynucleotides to cells CHIRON CORPORATION 2003-05-27 US claimed
US-6197332-B1 ACYLATION AND AMIDATION TO FORM POLYAMIDES FOR CONJUGATED LIPIDS CHIRON CORPORATION 2001-03-06 US claimed
EP-0317968-B1 Glycerides as charge directors for liquid electrostatic developers DU PONT (US) 1994-04-06 EP claimed
US-4886726-A UNIFORM, HIGH QUALITY COPY IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-12-12 US claimed
EP-0317968-A2 Glycerides as charge directors for liquid electrostatic developers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-31 EP claimed
CN-114085297-A Cyclo beta-1, 2-glucan and curcumin clathrate compound and preparation method thereof 江南大学 2022-02-25 CN disclosed
US-20210198671-A1 PROTECTED ANTIBODY-DRUG AND APTAMER-DRUG CONJUGATES KOSAK KENNETH MICHAEL (US) 2021-07-01 US disclosed
CN-108265090-B Preparation method of antarctic krill oil substitute 中粮集团有限公司 2021-06-15 CN disclosed
CN-106893747-B Preparation method of PLA1 type n-3 polyunsaturated fatty acid phospholipid 中粮集团有限公司 2021-03-05 CN disclosed
US-20120149940-A1 Integrin Modulators and Methods for Their Use BILLINGS PHARMACEUTICALS, INC. 2012-06-14 US disclosed
EP-0317968-B1 Glycerides as charge directors for liquid electrostatic developers DU PONT (US) 1994-04-06 EP disclosed
US-4981957-A VIRICIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1991-01-01 US disclosed
US-4886726-A UNIFORM, HIGH QUALITY COPY IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-12-12 US disclosed
EP-0317968-A2 Glycerides as charge directors for liquid electrostatic developers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-31 EP disclosed
EP-0169775-B1 OLIGONUCLEOTIDES, PROCESS FOR THEIR PREPARATION AND THEIR USES AS MEDIATORS IN THE ENHANCEMENT OF THE EFFECTS OF INTERFERONS Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-05-24 EP disclosed
EP-0169775-A1 Oligonucleotides, process for their preparation and their uses as mediators in the enhancement of the effects of interferons Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149940-A1 Integrin Modulators and Methods for Their Use ITGA5, ITGB1, ITGB5 LMNA 2337/4885FDPS 1241/4885PDE3A 799/4885
US-20210198671-A1 PROTECTED ANTIBODY-DRUG AND APTAMER-DRUG CONJUGATES ZFR, APP, RBM26 LMNA 1504/4885FDPS 2741/4885PDE3A 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.