Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 5/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303883 | 1.00 | SLC7A5 (0.50) | SLC7A5ALDH1A1BACE1CTSDFNTA | |
| SCHEMBL9551440 | 0.97 | SLC7A5 (0.47) | SLC7A5ALDH1A1BACE1CTSDFNTA | |
| SCHEMBL10621390 | 0.97 | SLC7A5 (0.47) | SLC7A5ALDH1A1BACE1CTSDFNTA | |
| SCHEMBL29591958 | 0.93 | BACE1 (0.47) | SLC7A5BACE1CTSDFNTAFNTB | |
| SCHEMBL30753843 | 0.93 | FNTA (0.47) | SLC7A5ALDH1A1BACE1CTSDFNTA | |
| SCHEMBL30584447 | 0.92 | BACE1 (0.47) | SLC7A5ALDH1A1BACE1CTSDFNTA | |
| Leu-Ala SCHEMBL259115 | 0.91 | SLC7A5 (0.59) | SLC7A5ALDH1A1BACE1CTSDMAPT | |
| Leu-Ala SCHEMBL14117889 | 0.91 | SLC7A5 (0.59) | SLC7A5ALDH1A1BACE1CTSDMAPT | |
| Leu-Ala SCHEMBL2030930 | 0.91 | SLC7A5 (0.59) | SLC7A5ALDH1A1BACE1CTSDMAPT | |
| Leu-Ala SCHEMBL31696288 | 0.91 | SLC7A5 (0.59) | SLC7A5ALDH1A1BACE1CTSDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113747-A1 | Coupling of Antibody Polypeptides at the C-Terminus | NOVO NORDISK A/S (DK) | 2010-05-06 | — | — | US | disclosed |
| EP-2115001-A1 | COUPLING OF ANTIBODY POLYPEPTIDES AT THE C-TERMINUS | Novo Nordisk A/S (DK) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008107260-A1 | COUPLING OF ANTIBODY POLYPEPTIDES AT THE C-TERMINUS | NOVO NORDISK A/S (DK) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113747-A1 | Coupling of Antibody Polypeptides at the C-Terminus | FCGRT, FCGR3B, FCGR2A | SLC7A5 4103/4885ALDH1A1 4747/4885BACE1 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.