Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378246 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1PKMHPGD | |
| SCHEMBL107871 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| SCHEMBL27957517 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| SCHEMBL29409551 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| SCHEMBL29581540 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| SCHEMBL12708541 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| Hydrochloric Acid SCHEMBL6062984 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1PKMHPGD | |
| Hydrochloric Acid SCHEMBL8642202 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| SCHEMBL10013562 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4ETDP1PKMCASP1 | |
| SCHEMBL1755260 | 0.80 | PDE2A (0.46) | ALDH1A1MAPTTSHRMAPK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592425-A | Cycloheptatriene-base rare-earth metal catalyst, and preparation method and application thereof | BEIJING INST TECHNOLOGY | 2015-05-06 | — | — | CN | claimed |
| US-8288552-B2 | Dihydropyridone amidesas P2X7 modulators | ROCHE PALO ALTO LLC (US) | 2012-10-16 | — | — | US | claimed |
| CN-102491906-A | Synthetic method for 2-methyl-3-trifluoromethyl phenylamine | QILU ANIMAL HEALTH PRODUCTS CO | 2012-06-13 | — | — | CN | claimed |
| CN-102442944-A | Preparation method of flunixin | QILU ANIMAL HEALTH CARE PRODUCTS CO LTD | 2012-05-09 | — | — | CN | claimed |
| JP-2045451-A | — | — | None | — | — | JP | disclosed |
| JP-63270631-A | — | — | None | — | — | JP | disclosed |
| JP-63270632-A | — | — | None | — | — | JP | disclosed |
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| CN-111699176-B | Quinazolinones as PARP14 inhibitors | 里邦医疗公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20240262842-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | MERCK SHARP & DOHME LLC | 2024-08-08 | — | — | US | disclosed |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2024-07-18 | — | — | US | disclosed |
| CN-1030577-A | Disinsection method with 2-phenylimidazole derivative | MAY & BAKER CO LTD (GB) | 1989-01-25 | — | — | CN | disclosed |
| JP-S63270632-A | NOVEL DICHLOROTRIFLUOROMETHYLTOLUENE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-11-08 | — | — | JP | disclosed |
| JP-S63270631-A | NOVEL DICHLOROTRICHLOROMETHYLTOLUENE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-11-08 | — | — | JP | disclosed |
| EP-0283173-A1 | Pesticidal method using 2-phenylimidazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |
| US-4132737-A | ENZYME INHIBITORS | ELI LILLY AND COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4046554-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-3966811-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
| US-3960890-A | CONTROL OF ECTOPARASITES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239788-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT | KRAS, NRAS, HRAS | ALDH1A1 2871/4885KDM4E 3110/4885TDP1 2748/4885 |
| US-20240262842-A1 | SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT | KRAS, NRAS, HRAS | ALDH1A1 1875/4885KDM4E 3441/4885TDP1 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.