Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413893 | 0.91 | ADORA3 (0.46) | RXFP1FYNADORA3MEN1MAPK1 | |
| SCHEMBL412790 | 0.88 | NPSR1 (0.41) | LTB4RKMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3303665 | 0.87 | NPC1 (0.39) | RXFP1MEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL411938 | 0.86 | PDE4A (0.39) | RXFP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL407568 | 0.86 | LMNA (0.40) | RXFP1FYNADORA3MEN1MAPK1 | |
| SCHEMBL13041260 | 0.86 | NPSR1 (0.50) | LTB4RKDM4EALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4629523 | 0.86 | LMNA (0.40) | RXFP1FYNADORA3MEN1MAPK1 | |
| SCHEMBL413515 | 0.86 | EGFR (0.43) | LTB4RMEN1KMT2ATUBB4ATUBB | |
| SCHEMBL3300296 | 0.86 | NPSR1 (0.43) | RXFP1LTB4RKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL412792 | 0.86 | LMNA (0.40) | RXFP1FYNADORA3MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093670-A1 | Compounds for the treatment of angiogenesis | SYNTA PHARMACEUTICALS CORP. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093670-A1 | Compounds for the treatment of angiogenesis | FLT4, FLT1, TEK | RXFP1 265/4885FYN 2710/4885LTB4R 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.