Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305137 | 1.00 | HDAC3 (0.49) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL11033807 | 0.95 | EGFR (0.51) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL29196142 | 0.93 | EGFR (0.54) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL6668098 | 0.93 | EGFR (0.54) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL29196143 | 0.93 | EGFR (0.54) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL10626637 | 0.93 | EGFR (0.54) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL9779076 | 0.93 | EGFR (0.54) | HDAC3PRMT1RAB9AHTTEGFR | |
| Ammonia Solution, Strong SCHEMBL18037670 | 0.92 | EGFR (0.52) | HDAC3PRMT1RAB9AHTTEGFR | |
| Hydrochloric Acid SCHEMBL8663857 | 0.92 | EGFR (0.52) | HDAC3PRMT1RAB9AHTTEGFR | |
| SCHEMBL3299029 | 0.89 | RAB9A (0.50) | HDAC3PRMT1RAB9AEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724682-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-08 | — | — | US | disclosed |
| US-9724682-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-16 | — | — | US | disclosed |
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-16 | — | — | US | disclosed |
| US-9487472-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-08 | — | — | US | disclosed |
| US-9487472-B2 | Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160002145-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD (US) | 2016-01-07 | — | — | US | disclosed |
| US-20160002145-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD (US) | 2016-01-07 | — | — | US | disclosed |
| WO-2014134141-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-04 | — | — | WO | disclosed |
| US-8399594-B2 | Blocked-isocyanate silicone resins | DOW CORNING CORPORATION (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100093902-A1 | Blocked-Isocyanate Silicone Resins | DOW CORNING CORPORATION | 2010-04-15 | — | — | US | disclosed |
| EP-2102286-A1 | BLOCKED ISOCYANATE SILICONE RESINS | Dow Corning Corporation (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008088492-A1 | BLOCKED ISOCYANATE SILICONE RESINS | DOW CORNING CORPORATRION (US) | 2008-07-24 | — | — | WO | disclosed |
| US-20070167587-A1 | Process for producing polymer with functional end | KURARAY CO., LTD. (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1721912-A1 | PROCESS FOR PRODUCING POLYMER WITH FUNCTIONAL END | KURARAY CO., LTD. (JP) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | FTH1, FLI1, FECH | HDAC3 1698/4885PRMT1 185/4885RAB9A 3517/4885 |
| US-20160002145-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | FTH1, FLI1, FECH | HDAC3 1698/4885PRMT1 185/4885RAB9A 3517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.