SCHEMBL125680

SCHEMBL125680

CN(O)C(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.54
HSD11B1 P28845 1/20 0.53
HPGD P15428 2/20 0.48
ALDH1A1 P00352 2/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
DAO P14920 1/20 0.48
TSHR P16473 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 1/20 0.47
RECQL P46063 1/20 0.47
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3305633 0.91 HPGD (0.62) HSD11B1HPGDALDH1A1RAB9ANPC1
SCHEMBL3282793 0.87 HPGD (0.50) HSD11B1HPGDALDH1A1KMT2AKDM4E
SCHEMBL23169174 0.87 MAPT (0.61) HPGDALDH1A1RAB9ANPC1KDM4E
SCHEMBL3279166 0.83 KMT2A (0.53) HSP90AA1HPGDKMT2AMEN1
SCHEMBL4039494 0.82 ALDH1A1 (0.58) HSD11B1HPGDALDH1A1RAB9ANPC1
SCHEMBL11211866 0.82 HSD11B1 (0.55) HSD11B1HPGDALDH1A1RAB9ANPC1
SCHEMBL30062 0.82 ALDH1A1 (0.58) HSD11B1HPGDALDH1A1RAB9ANPC1
SCHEMBL2220361 0.82 ALDH1A1 (0.55) HSD11B1HPGDALDH1A1RAB9ANPC1
SCHEMBL9878124 0.82 SMN1; SMN2 (0.63) HSP90AA1HPGDALDH1A1RAB9ANPC1
SCHEMBL9877250 0.82 ATM (0.67) HPGDALDH1A1RAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106008193-B Method for catalytically oxidizing lignite by using oxygen as oxidant under normal pressure 中国矿业大学 2019-12-17 CN claimed
CN-110177783-A Hormone receptor modulators for the treatment of metabolic conditions and disorders 阿德利克斯股份有限公司 2019-08-27 CN claimed
US-10160712-B2 Method of catalytic oxidation of lignite using oxygen as oxidant at atmospheric pressure CHINA UNIVERSITY OF MINING AND TECHNOLOGY (CN) 2018-12-25 US claimed
US-20180237371-A1 METHOD OF CATALYTIC OXIDATION OF LIGNITE USING OXYGEN AS OXIDANT AT ATMOSPHERIC PRESSURE CHINA UNIVERSITY OF MINING AND TECHNOLOGY (CN) 2018-08-23 US claimed
CN-102856586-B Nonaqueous secondary battery and flame retardant for use in the same SHARP KK 2015-01-14 CN claimed
CN-1480132-A Protective solution for preventing local ischemic damage �����ġ����ղ�ʿ��ѧ���޹�˾ 2004-03-10 CN claimed
US-20030215781-A1 Protective solutions for organs DR. FRANZ KOEHLER CHEMIE GMBH (DE) 2003-11-20 US claimed
EP-1362511-A1 Protective solution for preventing ischaemia Dr. Franz Köhler Chemie GmbH (DE) 2003-11-19 EP claimed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 US claimed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 EP claimed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 EP claimed
CN-122010873-A Synthesis method of gem-diamine compound 合肥工业大学 2026-05-12 CN disclosed
US-20260118751-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION COMPRISING THE SAME, AND PATTERN FORMATION METHOD USING THE RESIST COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-30 US disclosed
CN-118344325-A PI3K selective inhibitors 轩竹生物科技股份有限公司 2024-07-16 CN disclosed
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF CORTEVA AGRISCIENCE LLC (US) 2024-04-18 US disclosed
US-5002853-A Polymeric Sulfonyloxy-Amides and Iides FUJI PHOTO FILM CO., LTD. (JP) 1991-03-26 US disclosed
EP-0410606-A2 Siloxane polymers and positive working light-sensitive compositions comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1991-01-30 EP disclosed
EP-0363198-A2 Positive working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed
EP-0115156-A2 Light sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1984-08-08 EP disclosed
US-4371605-A Photopolymerizable compositions containing N-hydroxyamide and N-hydroxyimide sulfonates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240122179-A1 AUXINIC HERBICIDES AND METHODS OF USE THEREOF DDT, HACL2, ALAD HSP90AA1 1106/4885HSD11B1 570/4885HPGD 2047/4885
US-10160712-B2 Method of catalytic oxidation of lignite using oxygen as oxidant at atmospheric pressure HAO2, EGLN2, CAPN9 HSP90AA1 2952/4885HSD11B1 204/4885HPGD 577/4885
US-20180237371-A1 METHOD OF CATALYTIC OXIDATION OF LIGNITE USING OXYGEN AS OXIDANT AT ATMOSPHERIC PRESSURE HAO2, ELL, NOX4 HSP90AA1 3054/4885HSD11B1 705/4885HPGD 1106/4885
US-20260118751-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION COMPRISING THE SAME, AND PATTERN FORMATION METHOD USING THE RESIST COMPOSITION LBR, RER1, MNS1 HSP90AA1 4119/4885HSD11B1 2307/4885HPGD 4817/4885
US-20030215781-A1 Protective solutions for organs GLS, CA1, SI HSP90AA1 479/4885HSD11B1 2179/4885HPGD 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.