SCHEMBL330550

SCHEMBL330550

C1=CNc2ccccc2N=C1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRK6 P43250 1/20 0.34
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
PPARG P37231 1/20 0.31
KMT2A Q03164 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NR2E3 Q9Y5X4 1/20 0.31
NCOR2 Q9Y618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9958734 1.00 GRK6 (0.34) GRK6MEN1USP2PPARGKMT2A
SCHEMBL9958738 1.00 GRK6 (0.34) GRK6MEN1USP2PPARGKMT2A
SCHEMBL2903859 1.00 GRK6 (0.34) GRK6MEN1USP2PPARGKMT2A
Hydrochloric Acid SCHEMBL5739950 0.98 GRK6 (0.33) GRK6MEN1USP2PPARGKMT2A
Hydrochloric Acid SCHEMBL7477355 0.98 GRK6 (0.33) GRK6MEN1USP2PPARGKMT2A
SCHEMBL27344588 0.98 GRK6 (0.33) GRK6MEN1USP2PPARGKMT2A
Hydrochloric Acid SCHEMBL28741046 0.96 GRK6 (0.32) GRK6
SCHEMBL6300819 0.77 KDM4E (0.31)
SCHEMBL6300812 0.77
SCHEMBL30218263 0.70 TRPA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 732 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. 2025-03-06 US claimed
EP-4463153-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION Eleusis Therapeutics US, Inc. (US) 2024-11-20 EP claimed
CN-114276304-B A process for preparing 1, 5-benzodiazepine derivatives as pharmaceutical intermediates containing fused rings 南京苏亦欣医药科技有限公司 2024-07-02 CN claimed
CN-118221679-A Benzo [ b ] [1,4] diazepine [4,5-e ] tetrazole derivative and pharmaceutically acceptable salt, preparation method and application thereof 常熟理工学院 2024-06-21 CN claimed
CN-116589417-B method for green synthesis of medical intermediate 1, 5-benzodiazepine derivative 安徽工业大学 2024-03-26 CN claimed
CN-117105934-A Method for preparing benzodiazepine compound by selective hydrogenation 石河子大学 2023-11-24 CN claimed
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION ELEUSIS THERAPEUTICS US, INC. 2023-09-07 US claimed
CN-116589417-A Method for green synthesis of medical intermediate 1, 5-benzodiazepine derivative 安徽工业大学 2023-08-15 CN claimed
WO-2023137094-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION ELEUSIS THERAPEUTICS US, INC. (US) 2023-07-20 WO claimed
EP-4178569-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION Eleusis Therapeutics US, Inc. (US) 2023-05-17 EP claimed
US-6413930-B1 CONTROLLING EYE MOVEMENT GLAXO WELLCOME SPA (IT) 2002-07-02 US claimed
EP-0785788-B1 USE OF CCK-B RECEPTOR ANTAGONISTS FOR THE TREATMENT OF SLEEP DISORDERS GLAXO WELLCOME SPA (IT) 2001-12-12 EP claimed
CN-1307567-A 1,5 benzodiazepine derivatives ZERIA PHARM CO LTD (JP) 2001-08-08 CN claimed
EP-1085014-A1 1,5-BENZODIAZEPINE DERIVATIVES Zeria Pharmaceutical Co., Ltd. (JP) 2001-03-21 EP claimed
EP-0945445-A1 1,5-BENZODIAZEPINE DERIVATIVES ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-09-29 EP claimed
EP-0395323-B1 Process for preparing 1,5-benzothiazepine derivatives TANABE SEIYAKU CO (JP) 1997-06-11 EP claimed
EP-0487155-A1 Substituted-2,3-dihydro-2-oxo-1,5-benzodiazepines and their use as fungicides EASTMAN KODAK COMPANY (US) 1992-05-27 EP claimed
EP-0211429-A1 1,5-Benzodiazepine compounds E.R. Squibb & Sons, Inc. (US) 1987-02-25 EP claimed
US-4036649-A Silver halide emulsion sensitized with a fused diazepine E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-07-19 US claimed
US-3984398-A 1,5-Benzodiazepine-2,4-diones ROUSSEL-UCLAF (FR) 1976-10-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250073207-A1 PSILOCIN BENZOATE FORMULATION FOR INTRAVENOUS INFUSION SRI, PROC, PRDX6 GRK6 3601/4885MEN1 4470/4885USP2 2834/4885
US-20230277568-A1 METHOD OF TREATMENT FOR PSILOCYBIN OR PSILOCIN INFUSION PNN, HTR1B, GABBR1 GRK6 980/4885MEN1 2910/4885USP2 3791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.