Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 4/20 | 0.47 |
| ▸ | NOS3 | P29474 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | OGT | O15294 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535312 | 0.82 | MCL1 (0.47) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL31180324 | 0.81 | MCL1 (0.46) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL23209073 | 0.81 | MCL1 (0.46) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL5535318 | 0.81 | MCL1 (0.46) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL16176728 | 0.81 | MCL1 (0.46) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL2062117 | 0.77 | F2 (0.43) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL24858181 | 0.77 | MCL1 (0.42) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL10884377 | 0.76 | KMO (0.55) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL5077255 | 0.76 | PSMB8 (0.61) | MCL1NOS1NOS3NOS2LMNA | |
| SCHEMBL30146353 | 0.76 | PSMB8 (0.61) | MCL1NOS1NOS3NOS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111526873-B | For modulating microbial colonization substituted diphenylacetylenes of (2) | 生物曼迪克斯有限责任公司 | 2025-03-04 | — | — | CN | claimed |
| CN-109294483-B | Sealant applied to sealing of underwater optical electronic equipment and preparation method thereof | 中国航发北京航空材料研究院 | 2021-03-26 | — | — | CN | claimed |
| CN-111526873-A | Substituted tolanes for regulating microbial colonization | 生物曼迪克斯有限责任公司 | 2020-08-11 | — | — | CN | claimed |
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2020-07-02 | — | — | US | claimed |
| EP-3658128-A1 | SUBSTITUTED TOLANS FOR THE MODULATION OF MICROBIAL COLONIZATION | Biomendics, LLC (US) | 2020-06-03 | — | — | EP | claimed |
| CN-109294483-A | A kind of sealant and preparation method thereof applied to the sealing of underwater optics electronic equipment | 中国航发北京航空材料研究院 | 2019-02-01 | — | — | CN | claimed |
| WO-2019023425-A1 | SUBSTITUTED TOLANS FOR THE MODULATION OF MICROBIAL COLONIZATION | BioMendics, LLC (US) | 2019-01-31 | — | — | WO | claimed |
| CN-105089232-B | A kind of multi-layer compound structure flexibility veneer products and its production method | 上海古猿人石材有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-105885676-A | Damp-proof and mildew-resistant coating and preparation method thereof | 陕西宝成航空仪表有限责任公司 | 2016-08-24 | — | — | CN | claimed |
| CN-101969771-A | Antimicrobial compositions, methods and systems | ELEVANCE RENEWABLE SCIENCES | 2011-02-09 | — | — | CN | claimed |
| EP-2007199-A2 | ANTIMICROBIAL COMPOSITIONS, METHODS AND SYSTEMS | Elevance Renewable Sciences, Inc. (US) | 2008-12-31 | — | — | EP | claimed |
| US-20080033026-A1 | Antimicrobial compositions, methods and systems | ELEVANCE RENEWABLE SCIENCES, INC. | 2008-02-07 | — | — | US | claimed |
| WO-2007092633-A2 | ANTIMICROBIAL COMPOSITIONS, METHODS AND SYSTEMS | ELEVANCE RENEWABLE SCIENCES, INC. (US) | 2007-08-16 | — | — | WO | claimed |
| CN-111526873-B | For modulating microbial colonization substituted diphenylacetylenes of (2) | 生物曼迪克斯有限责任公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-217955477-U | Mould-proof torsion-resistant medium-voltage wind energy cable | 中天科技装备电缆有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20220296538-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2022-09-22 | — | — | US | disclosed |
| US-4339462-A | BACTERICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0038109-A2 | Agents and method for the protection of coatings and wood and other non-living organic substrates from deterioration by micro-organisms | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-10-21 | — | — | EP | disclosed |
| EP-0031795-A1 | Hydroxyphenyl ketones | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |
| US-4268693-A | 3-Hydroxydiphenyl ethers | CIBA-GEIGY CORPORATION (US) | 1981-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | LMAN1, DPM1, DSTN | MCL1 98/4885NOS1 2809/4885NOS3 2946/4885 |
| US-20080033026-A1 | Antimicrobial compositions, methods and systems | DHCR7, SPOUT1, DSTN | MCL1 1416/4885NOS1 385/4885NOS3 410/4885 |
| US-20220296538-A1 | Substituted Tolans for the Modulation of Microbial Colonization | LMAN1, DPM1, DSTN | MCL1 98/4885NOS1 2809/4885NOS3 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.