Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 4/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306286 | 1.00 | CCNK (0.49) | CCNKCDK12F10PDE4BMCHR1 | |
| SCHEMBL3311823 | 0.86 | KDM5A (0.54) | CCNKCDK12F10MCHR1L3MBTL3 | |
| SCHEMBL3311825 | 0.86 | KDM5A (0.54) | CCNKCDK12F10MCHR1L3MBTL3 | |
| SCHEMBL3308274 | 0.84 | KDM5A (0.55) | CCNKCDK12ALDH1A1L3MBTL1 | |
| SCHEMBL3308282 | 0.84 | KDM5A (0.55) | CCNKCDK12ALDH1A1L3MBTL1 | |
| SCHEMBL3308077 | 0.83 | F10 (0.48) | CCNKCDK12F10MCHR1KDM1A | |
| SCHEMBL3308085 | 0.83 | F10 (0.48) | CCNKCDK12F10MCHR1KDM1A | |
| SCHEMBL13395041 | 0.83 | CCNK (0.43) | CCNKCDK12F10ALDH1A1 | |
| SCHEMBL3307390 | 0.83 | KDM5A (0.55) | CCNKCDK12F10PDE4BL3MBTL1 | |
| SCHEMBL3307385 | 0.83 | KDM5A (0.55) | CCNKCDK12F10PDE4BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309542-B2 | Substituted pyrrolidine amides, the production thereof, and the use thereof as medications | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20100099664-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099664-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | DDC, GLS, UROD | CCNK 1866/4885CDK12 2491/4885F10 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.