Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408751 | 0.91 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL4108908 | 0.89 | LMNA (0.47) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL411380 | 0.88 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL3302673 | 0.88 | ALDH1A1 (0.48) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL412945 | 0.87 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL10189689 | 0.87 | NPSR1 (0.49) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL407548 | 0.87 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL411212 | 0.86 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL3302459 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL412381 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093670-A1 | Compounds for the treatment of angiogenesis | SYNTA PHARMACEUTICALS CORP. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093670-A1 | Compounds for the treatment of angiogenesis | FLT4, FLT1, TEK | LMNA 4831/4885ALDH1A1 414/4885SMN1; SMN2 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.