SCHEMBL3306609

SCHEMBL3306609

CC=CC(=O)OCCC[SiH](O)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.44
AKR1B10 O60218 7/20 0.43
AKR1B1 P15121 7/20 0.43
ALOX5 P09917 4/20 0.41
MAOB P27338 1/20 0.39
LMNA P02545 3/20 0.38
TTR P02766 2/20 0.38
CYP3A4 P08684 2/20 0.37
ALOX15 P16050 2/20 0.37
ALOX12 P18054 2/20 0.37
MAPK1 P28482 2/20 0.37
HSD17B10 Q99714 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
GMNN O75496 1/20 0.37
ALDH1A1 P00352 1/20 0.37
EGFR P00533 1/20 0.37
ESR1 P03372 1/20 0.37
ERBB2 P04626 1/20 0.37
APP P05067 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306606 0.77 TDP1 (0.49) LMNACYP3A4MAPK1KDM4EALDH1A1
SCHEMBL1845409 0.76 HCAR2 (0.73) HCAR2AKR1B10AKR1B1ALOX5MAOB
SCHEMBL1845413 0.76 HCAR2 (0.73) HCAR2AKR1B10AKR1B1ALOX5MAOB
SCHEMBL10886450 0.75 AKR1B10 (0.58) HCAR2AKR1B10AKR1B1ALOX5MAOB
SCHEMBL7889614 0.74 MAPT (0.38) HCAR2AKR1B10AKR1B1ALOX5LMNA
SCHEMBL7884066 0.73 ATM (0.40) HCAR2AKR1B10AKR1B1LMNACYP3A4
SCHEMBL1070426 0.73 HCAR2 (0.71) HCAR2AKR1B10AKR1B1LMNATTR
SCHEMBL4448964 0.73 ATM (0.47) HCAR2CYP3A4ALDH1A1APPMAPT
SCHEMBL1070423 0.73 HCAR2 (0.71) HCAR2AKR1B10AKR1B1LMNATTR
SCHEMBL2468781 0.72 ATM (0.50) HCAR2CYP3A4ALDH1A1APPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595926-B1 COATING COMPOSITION DAIKIN IND LTD (JP) 2014-03-26 EP disclosed
US-8293840-B2 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2012-10-23 US disclosed
US-7807752-B2 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2010-10-05 US disclosed
US-20100113662-A1 COATING COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
US-20060054053-A1 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
EP-1595926-A1 COATING COMPOSITION Daikin Industries, Ltd. (JP) 2005-11-16 EP disclosed
EP-1153983-B1 Top coating composition NIPPON PAINT CO LTD (JP) 2005-06-15 EP disclosed
EP-1160295-B1 Clear coatings, and method of forming multilayer coatings NIPPON PAINT CO LTD (JP) 2005-06-01 EP disclosed
US-6767984-B2 FILM- FORMING RESIN; SILICATE COMPOUND; HYDROLYZABLE SILYL-CONTAINING RESIN OR GRAFT POLYMER OF THE SILICATE ONTO THE HYDROLYZABLE SILYL-CONTAINING RESIN NIPPON PAINT CO., LTD. (JP) 2004-07-27 US disclosed
EP-0811669-B1 USE OF A FLUORSILICATE AS STAIN-PROOFING AGENT DAIKIN IND LTD (JP) 2004-02-04 EP disclosed
EP-0852251-A1 POLLUTANT DEPOSITION INHIBITOR AND COATING MATERIAL COMPOSITION DAIKIN INDUSTRIES, LIMITED (JP) 1998-07-08 EP disclosed
US-5721015-A CATALYST CURING MAZDA MOTOR CORPORATION (JP) 1998-02-24 US disclosed
EP-0811669-A1 ANTIFOULING AGENT AND NONAQUEOUS COATING COMPOSITION CONTAINING SAID AGENT DAIKIN INDUSTRIES, LIMITED (JP) 1997-12-10 EP disclosed
US-5525673-A LOW-TEMPERATURE CURING AUTOMOBILE TOPCOATS COMPRISING A BLEND OF SILICON-AND FLUORINE-CONTAINING ADDITION POLYMERS; STORAGE-STABLE ONE-PACKAGE; WEATHERPROOFING, WEAR RESISTANCE;ANTISOILANTS KANSAI PAINT COMPANY, LIMITED (JP) 1996-06-11 US disclosed
US-5418293-A Fluoropolymer, epoxy or silicone compound KANSAI PAINT COMPANY, LIMITED (JP) 1995-05-23 US disclosed
US-5408001-A Protective coatings KANSAI PAINT COMPANY, LIMITED (JP) 1995-04-18 US disclosed
US-5387646-A Protective coating; blend of an organosilicon and epoxy polymer KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-07 US disclosed
US-5260376-A Fluoropolymers, hydroxy-polymer, polysiloxanes KANSAI PAINT COMPANY, LIMITED (JP) 1993-11-09 US disclosed
US-5166265-A Protective coatings KANSAI PAINT COMPANY, LIMITED (JP) 1992-11-24 US disclosed
US-5130167-A For automobiles, vinyl polymers containing silicon groups, epoxy groups and hydroxy groups KANSAI PAINT COMPANY, LIMITED (JP) 1992-07-14 US disclosed