SCHEMBL3306606

SCHEMBL3306606

C=C(C)C(=O)OCCC[SiH](O)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.49
POLB P06746 1/20 0.49
APEX1 P27695 1/20 0.49
HTT P42858 1/20 0.49
TSHR P16473 3/20 0.43
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
THRB P10828 1/20 0.37
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ELANE P08246 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
RECQL P46063 1/20 0.35
RAB9A P51151 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3309530 0.84 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
SCHEMBL3305049 0.82 TDP1 (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL148938 0.79 LMNA (0.60) TDP1POLBAPEX1HTTTSHR
SCHEMBL146245 0.78 POLB (0.55) TDP1POLBAPEX1HTTTSHR
Lithium SCHEMBL30708617 0.78 LMNA (0.58) TDP1POLBAPEX1HTTTSHR
SCHEMBL3306609 0.77 HCAR2 (0.44) TDP1TSHRALDH1A1LMNACYP3A4
SCHEMBL342384 0.77 POLB (0.57) TDP1POLBAPEX1HTTTSHR
SCHEMBL4447342 0.77 POLB (0.57) TDP1POLBAPEX1HTTTSHR
SCHEMBL232155 0.77 POLB (0.57) TDP1POLBAPEX1HTTTSHR
SCHEMBL233287 0.77 POLB (0.57) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1595926-B1 COATING COMPOSITION DAIKIN IND LTD (JP) 2014-03-26 EP disclosed
US-8293840-B2 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2012-10-23 US disclosed
US-7807752-B2 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2010-10-05 US disclosed
US-20100113662-A1 COATING COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
US-20060054053-A1 Coating composition DAIKIN INDUSTRIES, LTD. (JP) 2006-03-16 US disclosed
EP-1595926-A1 COATING COMPOSITION Daikin Industries, Ltd. (JP) 2005-11-16 EP disclosed
EP-1153983-B1 Top coating composition NIPPON PAINT CO LTD (JP) 2005-06-15 EP disclosed
EP-1160295-B1 Clear coatings, and method of forming multilayer coatings NIPPON PAINT CO LTD (JP) 2005-06-01 EP disclosed
US-6767984-B2 FILM- FORMING RESIN; SILICATE COMPOUND; HYDROLYZABLE SILYL-CONTAINING RESIN OR GRAFT POLYMER OF THE SILICATE ONTO THE HYDROLYZABLE SILYL-CONTAINING RESIN NIPPON PAINT CO., LTD. (JP) 2004-07-27 US disclosed
EP-0811669-B1 USE OF A FLUORSILICATE AS STAIN-PROOFING AGENT DAIKIN IND LTD (JP) 2004-02-04 EP disclosed
US-5418293-A Fluoropolymer, epoxy or silicone compound KANSAI PAINT COMPANY, LIMITED (JP) 1995-05-23 US disclosed
US-5408001-A Protective coatings KANSAI PAINT COMPANY, LIMITED (JP) 1995-04-18 US disclosed
US-5389727-A Low temperature curing, weatherproofing KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-14 US disclosed
US-5387646-A Protective coating; blend of an organosilicon and epoxy polymer KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-07 US disclosed
US-5284919-A Low temperature curing, waterproofing, acid resistance KANSAI PAINT COMPANY, LIMITED (JP) 1994-02-08 US disclosed
US-5260376-A Fluoropolymers, hydroxy-polymer, polysiloxanes KANSAI PAINT COMPANY, LIMITED (JP) 1993-11-09 US disclosed
US-5166265-A Protective coatings KANSAI PAINT COMPANY, LIMITED (JP) 1992-11-24 US disclosed
US-5130167-A For automobiles, vinyl polymers containing silicon groups, epoxy groups and hydroxy groups KANSAI PAINT COMPANY, LIMITED (JP) 1992-07-14 US disclosed
US-5026793-A Containing hydroxy, epoxy, and silane compounds with chelate compound containing aluminum, titanium, or zironium KANSAI PAINT COMPANY LIMITED (JP) 1991-06-25 US disclosed
EP-0358238-A2 Resin compositions and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP disclosed