Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.78 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | CTSL | P07711 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30383105 | 1.00 | CYP19A1 (1.00) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL3307506 | 1.00 | CYP19A1 (1.00) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL3304113 | 0.93 | CYP19A1 (0.86) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL3304114 | 0.93 | CYP19A1 (0.86) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL30383825 | 0.93 | CYP19A1 (0.86) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL30384003 | 0.89 | CYP19A1 (0.80) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL3305507 | 0.89 | CYP19A1 (0.80) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL3305503 | 0.89 | CYP19A1 (0.80) | CYP19A1PTPN1MEN1KMT2AABCG2 | |
| SCHEMBL3309998 | 0.88 | CYP19A1 (0.78) | CYP19A1PTPN1ABCG2MAPTALDH1A1 | |
| SCHEMBL3310002 | 0.88 | CYP19A1 (0.78) | CYP19A1PTPN1ABCG2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-8946287-B2 | Chemotherapeutic flavonoids, and syntheses thereof | PURDUE RESEARCH FOUNDATION (US) | 2015-02-03 | — | — | US | disclosed |
| US-20100099755-A1 | CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2010-04-22 | — | — | US | disclosed |
| WO-2008076767-A1 | CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099755-A1 | CHEMOTHERAPEUTIC FLAVONOIDS, AND SYNTHESES THEREOF | NRAS, FAU, DPYD | CYP19A1 104/4885PTPN1 4272/4885MEN1 1129/4885 |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | CYP19A1 270/4885PTPN1 1308/4885MEN1 3367/4885 |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | SERPINC1, SERPINE1, SERPINH1 | CYP19A1 320/4885PTPN1 1520/4885MEN1 2457/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | CYP19A1 320/4885PTPN1 1520/4885MEN1 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.