SCHEMBL3307901

SCHEMBL3307901

NC(=O)c1cc(Cl)c(C(=O)n2c3ccc2cc3)c(Cl)c1.NC(=O)c1ccc(C(=O)n2c3ccc2cc3)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.41
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
MAP4K4 O95819 4/20 0.36
PARP1 P09874 3/20 0.35
PARP10 Q53GL7 2/20 0.34
PARP4 Q9UKK3 2/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
PARP15 Q460N3 1/20 0.34
PARP14 Q460N5 1/20 0.34
PARP16 Q8N5Y8 1/20 0.34
PARP11 Q9NR21 1/20 0.34
HPGD P15428 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
POLB P06746 2/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL174536 0.83 PARP10 (0.46) PARP1PARP10PARP4ALDH1A1KMT2A
Water SCHEMBL27561730 0.81 PARP10 (0.45) PARP1PARP10PARP4ALDH1A1KMT2A
Urea SCHEMBL11673195 0.81 PARP10 (0.45) PARP1PARP10PARP4ALDH1A1KMT2A
Hydrazine SCHEMBL28084706 0.81 PARP10 (0.45) PARP1PARP10PARP4ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL27677598 0.81 PARP10 (0.45) PARP1PARP10PARP4ALDH1A1KMT2A
SCHEMBL28344986 0.81 PARP10 (0.45) PARP1PARP10PARP4ALDH1A1KMT2A
SCHEMBL29120355 0.80 PARP1 (0.39) BCAT2MKNK1MKNK2MAP4K4PARP1
Benzene SCHEMBL28239358 0.79 MAPT (0.54) MKNK1MKNK2PARP1PARP10PARP4
SCHEMBL27836321 0.79 ALDH1A1 (0.50) BCAT2MKNK1MKNK2MAP4K4PARP10
SCHEMBL1460416 0.78 CA12 (0.48) MKNK1MKNK2MAP4K4PARP1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8323837-B2 Porous film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-04 US disclosed
US-8313865-B2 Separator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-11-20 US disclosed
EP-2144311-B1 SEPARATOR SUMITOMO CHEMICAL CO (JP) 2012-09-12 EP disclosed
US-20100159318-A1 LAMINATED POROUS FILM SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-06-24 US disclosed
US-20100112432-A1 SEPARATOR SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-05-06 US disclosed
US-20100099022-A1 SEPARATOR SUMITOMO CHEMCIAL COMPANY, LIMITED (JP) 2010-04-22 US disclosed
US-20100092754-A1 POROUS FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-15 US disclosed
EP-2151321-A1 LAMINATED POROUS FILM Sumitomo Chemical Company, Limited (JP) 2010-02-10 EP disclosed
EP-2144311-A1 SEPARATOR Sumitomo Chemical Company, Limited (JP) 2010-01-13 EP disclosed
EP-2133387-A1 POROUS FILM Sumitomo Chemical Company, Limited (JP) 2009-12-16 EP disclosed
EP-2131418-A1 SEPARATOR Sumitomo Chemical Company, Limited (JP) 2009-12-09 EP disclosed