SCHEMBL330807

SCHEMBL330807

S=C=NCCCSCCCN=C=S

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 9/20 0.65
MIF P14174 5/20 0.48
NAAA Q02083 1/20 0.48
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
BACH1 O14867 1/20 0.41
MAFK O60675 1/20 0.41
EGFR P00533 1/20 0.41
PTGS2 P35354 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
GSK3B P49841 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28836397 0.92 TRPA1 (0.67) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL331092 0.90 TRPA1 (0.68) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL7523727 0.89 TRPA1 (0.54) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL11854374 0.85
SCHEMBL11859234 0.85 NAAA (0.69) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL11727275 0.85 NAAA (0.69) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL331340 0.83 TRPA1 (0.65) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL330896 0.82 TRPA1 (0.50) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL330766 0.80 TRPA1 (0.48) TRPA1MIFNAAAALDH1A1LMNA
SCHEMBL668271 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146189-A1 ADHESIVE COMPOSITION, THE PREPARATION METHOD AND USE THEREOF COVESTRO DEUTSCHLAND AG (DE) 2026-05-28 US disclosed
EP-4748866-A1 AQUEOUS POLYURETHANE DISPERSIONS AND APPLICATIONS THEREOF Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
EP-4679147-A1 MULTILAYER BODY, OPTICAL ARTICLE, COATING LAYER-CONTAINING MULTILAYER BODY, LENS, EYEGLASSES, AND FILM FOR WINDOWS TOKUYAMA CORPORATION (JP) 2026-01-14 EP disclosed
US-20250355282-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-11-20 US disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
US-20250188215-A1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-06-12 US disclosed
EP-4565633-A1 ADHESIVE COMPOSITION, THE PREPARATION METHOD AND USE THEREOF Covestro Deutschland AG (DE) 2025-06-11 EP disclosed
EP-4560367-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2025-05-28 EP disclosed
CN-119630721-A Adhesive composition, preparation method and application thereof 科思创德国股份有限公司 2025-03-14 CN disclosed
CN-114206963-B Aqueous polyurethane dispersions 科思创德国股份有限公司 2025-02-14 CN disclosed
US-5352758-A Polythiourethane formed by reaction of specific mercaptan with polyisocyanate or polyisothiocyanate MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-10-04 US disclosed
EP-0351073-B1 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS (JP) 1994-09-21 EP disclosed
US-5283312-A Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-01 US disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146189-A1 ADHESIVE COMPOSITION, THE PREPARATION METHOD AND USE THEREOF PUF60, XRCC6, F7 TRPA1 2530/4885MIF 861/4885NAAA 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.