Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL1157375 | 0.91 | MAPT (0.39) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| SCHEMBL396149 | 0.89 | MAPT (0.40) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| Bromide SCHEMBL8614699 | 0.87 | MAPT (0.39) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| Hydrochloric Acid SCHEMBL316715 | 0.87 | MAPT (0.43) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| Fluoride Ion SCHEMBL15993970 | 0.87 | MAPT (0.39) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| Water SCHEMBL15994022 | 0.87 | MAPT (0.39) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| Hydrochloric Acid SCHEMBL19025641 | 0.87 | MAPT (0.39) | SLC22A16MAPTLMNAHSP90AA1MEN1 | |
| SCHEMBL5582502 | 0.78 | MAPT (0.44) | SLC22A16MAPTLMNAMEN1KMT2A | |
| Iodide SCHEMBL9630545 | 0.76 | CES2 (0.50) | MAPTLMNAHSP90AA1MEN1KMT2A | |
| Iodide SCHEMBL9630733 | 0.76 | CES2 (0.50) | MAPTLMNAHSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100101644-A1 | ELECTROLYTE COMPOSITION AND DYE-SENSITIZED SOLAR CELL (DSSC) COMPRISING THE SAME | TRIPOD TECHNOLOGY CORPORATION (TW) | 2010-04-29 | — | — | US | disclosed |