Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GMNN | O75496 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396149 | 0.98 | MAPT (0.40) | MAPTSLC22A16BLMLMNAGMNN | |
| Hydrochloric Acid SCHEMBL19025641 | 0.96 | MAPT (0.39) | MAPTSLC22A16BLMLMNAGMNN | |
| Water SCHEMBL15994022 | 0.96 | MAPT (0.39) | MAPTSLC22A16BLMLMNAGMNN | |
| Fluoride Ion SCHEMBL15993970 | 0.96 | MAPT (0.39) | MAPTSLC22A16BLMLMNAGMNN | |
| Iodide SCHEMBL1157375 | 0.96 | MAPT (0.39) | MAPTSLC22A16BLMLMNAGMNN | |
| Bromide SCHEMBL8614699 | 0.96 | MAPT (0.39) | MAPTSLC22A16BLMLMNAGMNN | |
| Glycerin SCHEMBL3308566 | 0.87 | SLC22A16 (0.41) | MAPTSLC22A16LMNAMEN1HSP90AA1 | |
| SCHEMBL5582502 | 0.86 | MAPT (0.44) | MAPTSLC22A16BLMGALR3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11298760 | 0.86 | CES2 (0.47) | MAPTBLMLMNAGMNNMAPK1 | |
| Hydrochloric Acid SCHEMBL16990768 | 0.84 | CES2 (0.50) | MAPTBLMLMNAGMNNMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111150849-A | Composition and preparation method and application thereof | 广州隽沐生物科技股份有限公司 | 2020-05-15 | — | — | CN | claimed |
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | BROADLEY KENNETH N | 2010-02-11 | — | — | US | claimed |
| EP-1317294-B2 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2009-09-02 | — | — | EP | claimed |
| EP-1317294-B1 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORP (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1355611-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | Closure Medical Corporation (US) | 2003-10-29 | — | — | EP | claimed |
| US-6620846-B1 | Containing biocompatible alkyl ester cyanoacrylate monomer and quaternary amine polymerization initiator | CLOSURE MEDICAL CORPORATION | 2003-09-16 | — | — | US | claimed |
| EP-1317294-A1 | ABSORBABLE ADHESIVE COMPOSITIONS | Closure Medical Corporation (US) | 2003-06-11 | — | — | EP | claimed |
| US-20020147462-A1 | Bronchial occlusion method and apparatus | CLOSURE MEDICAL CORPORATION | 2002-10-10 | — | — | US | claimed |
| WO-2002022072-A2 | BRONCHIAL OCCLUSION METHOD AND APPARATUS | CLOSURE MEDICAL CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002009785-A1 | ABSORBABLE ADHESIVE COMPOSITIONS | CLOSURE MEDICAL CORPORATION (US) | 2002-02-07 | — | — | WO | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| JP-1231887-A | — | — | None | — | — | JP | disclosed |
| EP-4724114-A1 | CYANOACRYLATE ADHESIVE KITS | Chemence, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |
| JP-H01231887-A | PREPARATION OF PROTEIN | DR KARL THOMAE GMBH | 1989-09-18 | — | — | JP | disclosed |
| EP-0315782-A2 | Method for the production of proteins | Dr. Karl Thomae GmbH (DE) | 1989-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | KIT, TEKT1, CUTA | MAPT 2821/4885SLC22A16 4804/4885BLM 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.