SCHEMBL330913

SCHEMBL330913

S=C=NCCCCCCN=C=S

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 6/20 0.74
MIF P14174 4/20 0.74
TRPA1 O75762 8/20 0.64
GSK3B P49841 1/20 0.58
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
BACH1 O14867 1/20 0.54
MAFK O60675 1/20 0.54
EGFR P00533 1/20 0.54
PTGS2 P35354 1/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233523 1.00 NAAA (0.74) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL27170957 1.00 NAAA (0.74) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL6697263 1.00 NAAA (0.74) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL2149597 1.00 NAAA (0.74) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL1999782 1.00 NAAA (0.74) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL7133119 1.00 NAAA (0.74) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL484045 0.96 MIF (0.68) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL1854857 0.89
SCHEMBL1457042 0.86 NAAA (1.00) NAAAMIFTRPA1GSK3BALDH1A1
SCHEMBL17889889 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119139563-A Double-layer aqueous polyurethane coating capable of continuously releasing riboflavin and anticoagulant and application thereof 北京富亿源生物科技有限公司 2024-12-17 CN claimed
CN-115725040-A High-strength polyurethane rigid foam material 万华化学集团股份有限公司 2023-03-03 CN claimed
US-20200354507-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS NOVOL, INC. 2020-11-12 US claimed
CN-111699207-A Cross-linked optical polymers based on sorbitol 诺韦尔有限公司 2020-09-22 CN claimed
US-10696778-B1 Methods of making polymers using isosorbide NOVOL, INC. (US) 2020-06-30 US claimed
US-20120244414-A1 NONAQUEOUS ELECTROLYTE BATTERY AND BATTERY PACK KABUSHIKI KAISHA TOSHIBA (JP) 2012-09-27 US claimed
EP-1404743-B1 FAST POLYMERIZABLE/CURABLE EPISULFIDE BASED COMPOSITION, POLYMERIZATION/CURING PROCESS AND OPTICAL ARTICLES RESULTING THEREFROM ESSILOR INT (FR) 2009-11-25 EP claimed
US-7616374-B2 Electrophoretic displays with improved high temperature performance SIPIX IMAGING, INC. (US) 2009-11-10 US claimed
EP-1608704-B1 THIOPHOSPHINE COMPOUNDS AND METHOD OF MAKING POLYMERISABLE COMPOSITIONS CONTAINING THEM AND THEIR USE FOR MAKING OPHTALMIC LENSES ESSILOR INT (FR) 2008-03-19 EP claimed
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US claimed
US-20040120024-A1 Electrophoretic displays with improved high temperature performance SIPIX IMAGING, INC. 2004-06-24 US claimed
WO-2004027507-A1 ELECTROPHORETIC DISPLAYS WITH IMPROVED HIGH TEMPERATURE PERFORMANCE SIPIX IMAGING, INC. (US) 2004-04-01 WO claimed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US claimed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US claimed
EP-1051480-A2 ENZYME ACTIVATED SUPPORTS FOR ENANTIOMERIC SEPARATIONS Pharm-Eco Laboratoires, Incorporated (US) 2000-11-15 EP claimed
WO-1999037754-A2 ENZYME ACTIVATED SUPPORTS FOR ENANTIOMERIC SEPARATIONS PHARM-ECO LABORATORIES, INC. (US) 1999-07-29 WO claimed
US-4371612-A Immobilization of biological material with an acrylonitrile polymer TOYO JOZO COMPANY, LTD. (JP) 1983-02-01 US claimed
US-4154913-A ADDITION POLYMER ENDCAPPED WITH POLYISOCYANATE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-15 US claimed
US-4138292-A ENZYMES OR MICROORGANISMS IN A SULFATED POLYSACCHARIDE GEL TANABE SEIYAKU CO., LTD. (JP) 1979-02-06 US claimed
US-4070344-A WITH POLYISOCYANATE, AMIDE, HYDROLYSIS THE FIRESTONE TIRE AND RUBBER COMPANY (US) 1978-01-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696778-B1 Methods of making polymers using isosorbide PUF60, MACF1, PPIE NAAA 1529/4885MIF 712/4885TRPA1 1297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.