Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31085527 | 1.00 | IDO1 (0.40) | IDO1AGXTCA3CA6CA5A | |
| SCHEMBL6441169 | 0.86 | MAPT (0.39) | IDO1AGXTSLC6A2SLC6A4KDM4E | |
| SCHEMBL5655880 | 0.86 | MPO (0.43) | IDO1AGXTCA3CA6CA5A | |
| SCHEMBL13548272 | 0.86 | MAPT (0.39) | IDO1AGXTPDE4APDE4BPDE4C | |
| SCHEMBL8121079 | 0.86 | IDO1 (0.35) | IDO1AGXTCA3CA6CA5A | |
| SCHEMBL4921376 | 0.86 | MPO (0.43) | IDO1AGXTCA3CA6CA5A | |
| SCHEMBL27310 | 0.86 | TYR (0.37) | IDO1AGXTCA3CA6CA5A | |
| SCHEMBL17355055 | 0.83 | F2RL1 (0.42) | TYR | |
| SCHEMBL7667398 | 0.83 | IDO1 (0.37) | IDO1AGXTCA3CA6CA5A | |
| SCHEMBL16961174 | 0.83 | F2RL1 (0.42) | PDE4APDE4BPDE4CPDE4DTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4644384-A1 | CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Lichun Biotech Co., Ltd. (CN) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024146383-A1 | CYP11A1 INHIBITOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海闻耐医药科技有限公司 | 2024-07-11 | — | — | WO | disclosed |
| CN-118307519-A | CYP11A1 inhibitor compound, preparation method and application thereof | 上海闻耐医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| US-11312726-B2 | Thienodiazepine derivatives and application thereof | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2022-04-26 | — | — | US | disclosed |
| US-20210024605-A1 | CYCLIC PEPTIDE ANALOGS OF MELANOCORTIN AND AMANITIN AND METHODS OF MAKING SUCH | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2021-01-28 | — | — | US | disclosed |
| US-20210017190-A1 | THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2021-01-21 | — | — | US | disclosed |
| US-20200239452-A1 | IDO/TDO Inhibitor | CANBAS CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | disclosed |
| CN-101679346-B | Substituted benzoylamino-indan-2-carboxylic acids and related compounds | SANOFI-AVENTIS (FR) | 2014-10-22 | — | — | CN | disclosed |
| US-8569535-B2 | Substituted benzoylamino-indan-2-carboxylic acids and related compounds | SANOFI (FR) | 2013-10-29 | — | — | US | disclosed |
| WO-2008151211-A1 | SUBSTITUTED BENZOYLAMINO-INDAN-2-CARBOXYLIC ACIDS AND RELATED COMPOUNDS | SANOFI-AVENTIS (FR) | 2008-12-11 | — | — | WO | disclosed |
| US-7220743-B2 | Heterocyclic CB1 receptor antagonists | HOFFMANN-LA ROCHE INC. (US) | 2007-05-22 | — | — | US | disclosed |
| US-7067540-B2 | Substituted pyridinones | PHARMACIA CORPORATION (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050176775-A1 | Substituted pyridinones | PHARMACIA CORPORATION | 2005-08-11 | — | — | US | disclosed |
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20040058964-A1 | Substituted pyridinones | PHARMACIA LLC | 2004-03-25 | — | — | US | disclosed |
| EP-0238753-B1 | N-SUBSTITUTED CONDENSED POLYMETHYLENE IMINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-01-15 | — | — | EP | disclosed |
| US-4959374-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS, GLAUCOMA, HYPERGLYCEMIC AGENTS, ANTIDEPRESSANTS | BEECHAM GROUP P.L.C. (GB) | 1990-09-25 | — | — | US | disclosed |
| US-4863946-A | HYPOGLYCEMIC AND HYPOTENSIVE AGENTS | BEECHAM GROUP PLC (GB) | 1989-09-05 | — | — | US | disclosed |
| EP-0238753-A1 | N-substituted condensed polymethylene imine derivatives | BEECHAM GROUP PLC (GB) | 1987-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017190-A1 | THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF | BRD4, BRD3, BRD2 | IDO1 609/4885AGXT 3749/4885CA3 3786/4885 |
| US-20040058964-A1 | Substituted pyridinones | MAPK1, MAPK6, MAPK7 | IDO1 1657/4885AGXT 2941/4885CA3 4873/4885 |
| US-20200239452-A1 | IDO/TDO Inhibitor | IDO1, IDO2, TDO2 | IDO1 1/4885AGXT 263/4885CA3 629/4885 |
| US-20210024605-A1 | CYCLIC PEPTIDE ANALOGS OF MELANOCORTIN AND AMANITIN AND METHODS OF MAKING SUCH | MC3R, MC5R, MC4R | IDO1 300/4885AGXT 2366/4885CA3 1202/4885 |
| US-11312726-B2 | Thienodiazepine derivatives and application thereof | BRD4, BRD3, BRD2 | IDO1 609/4885AGXT 3749/4885CA3 3786/4885 |
| US-20050176775-A1 | Substituted pyridinones | MAPK1, MAPK6, MAP3K6 | IDO1 1267/4885AGXT 2620/4885CA3 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.