Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11667153 | 0.85 | KDM4E (0.54) | ALDH1A1GAAKDM4ELMNAMAPT | |
| SCHEMBL869669 | 0.85 | PTGDR2 (0.64) | ALDH1A1GAAL3MBTL1KDM4ELMNA | |
| SCHEMBL22701022 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4ELMNAMAPT | |
| SCHEMBL7329095 | 0.84 | KDM4E (0.56) | ALDH1A1GAAKDM4ELMNAMAPT | |
| SCHEMBL5098541 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAAL3MBTL1KDM4ELMNA | |
| SCHEMBL18062275 | 0.81 | L3MBTL1 (0.59) | ALDH1A1GAAL3MBTL1LMNAMAPT | |
| SCHEMBL19001359 | 0.81 | L3MBTL1 (0.62) | GAAL3MBTL1KDM4EMAPTSMN1; SMN2 | |
| Phosphoric Acid SCHEMBL29253402 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1KDM4ELMNA | |
| SCHEMBL11552066 | 0.81 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4ELMNAADRB2 | |
| SCHEMBL4209605 | 0.80 | GAA (0.54) | ALDH1A1GAAKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536344-B2 | Metathesis catalysts | UMICORE AG & CO. KG (DE) | 2013-09-17 | — | — | US | disclosed |
| US-20130211096-A1 | Novel Metathesis Catalysts | ARLT DIETER (DE) | 2013-08-15 | — | — | US | disclosed |
| US-8288558-B2 | Metathesis catalysts | UMICORE AG & CO. KG (DE) | 2012-10-16 | — | — | US | disclosed |
| US-20100113795-A1 | NOVEL METATHESIS CATALYSTS | UMICORE AG & CO. KG (DE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113795-A1 | NOVEL METATHESIS CATALYSTS | CYP1B1, CYP51A1, CYP1A1 | ALDH1A1 233/4885GAA 1995/4885L3MBTL1 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.