Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.46 |
| ▸ | CA1 | P00915 | 12/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15662298 | 0.82 | — | — | |
| SCHEMBL26318922 | 0.81 | DNM1 (0.39) | CA2CA1CA12CA14CA9 | |
| SCHEMBL11036549 | 0.79 | TP53 (0.42) | CA2CA1CA12CA14CA9 | |
| SCHEMBL293336 | 0.78 | CA2 (0.68) | CA2CA1CA12CA14CA9 | |
| SCHEMBL25129256 | 0.76 | CA2 (0.65) | CA2CA1CA12CA14CA9 | |
| SCHEMBL15546426 | 0.76 | CA2 (0.65) | CA2CA1CA12CA14CA9 | |
| SCHEMBL3790104 | 0.76 | CA2 (0.65) | CA2CA1CA12CA14CA9 | |
| SCHEMBL23319282 | 0.76 | CA2 (0.65) | CA2CA1CA12CA14CA9 | |
| SCHEMBL3793002 | 0.76 | CA2 (0.65) | CA2CA1CA12CA14CA9 | |
| SCHEMBL291781 | 0.76 | CA2 (0.46) | CA2CA1CA12CA14CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4150623-A2 | METHODS AND SYSTEMS FOR MACHINE LEARNING ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISMS IN LUPUS | Ampel Biosolutions, LLC (US) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021231713-A2 | METHODS AND SYSTEMS FOR MACHINE LEARNING ANALYSIS OF SINGLE NUCLEOTIDE POLYMORPHISMS IN LUPUS | AMPEL BIOSOLUTIONS, LLC (US) | 2021-11-18 | — | — | WO | disclosed |
| EP-3881233-A1 | MACHINE LEARNING DISEASE PREDICTION AND TREATMENT PRIORITIZATION | Ampel Biosolutions, LLC (US) | 2021-09-22 | — | — | EP | disclosed |
| US-20210104321-A1 | MACHINE LEARNING DISEASE PREDICTION AND TREATMENT PRIORITIZATION | UNITED BANK | 2021-04-08 | — | — | US | disclosed |
| WO-2020102043-A1 | MACHINE LEARNING DISEASE PREDICTION AND TREATMENT PRIORITIZATION | AMPEL BIOSOLUTIONS, LLC (US) | 2020-05-22 | — | — | WO | disclosed |
| US-7718652-B2 | Substituted benzothiadiazinedioxide derivatives and methods of their use | WYETH LLC (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080161295-A1 | SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
| WO-2008073958-A2 | SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161295-A1 | SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A2, SLC6A4, DBH | CA2 3013/4885CA1 3579/4885CA12 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.