Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253269 | 0.89 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL1961847 | 0.83 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL2458909 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL27787953 | 0.81 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL1552722 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL1552719 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL28212077 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL3325239 | 0.80 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL10714377 | 0.80 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL16758804 | 0.80 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814012-B | The preparation method of two alpha substituted benzylamines, the particularly dialkyl benzylamine of halo of halo | 拜耳作物科学股份公司 | 2018-01-26 | — | — | CN | disclosed |
| EP-3080070-B1 | METHOD FOR THE PREPARATION OF HALOGENATED DI-SUBSTITUTED BENZYLAMINES, IN PARTICULAR HALOGENETED DIALKYLBENZYLAMINES | BAYER CROPSCIENCE AG (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9670135-B2 | Preparation of halogenated di-substituted benzylamines, particularly halogenated dialkylbenzylamines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-06 | — | — | US | disclosed |
| US-20160304435-A1 | PREPARATION OF HALOGENATED DI-SUBSTITUTED BENZYLAMINES, PARTICULARLY HALOGENATED DIALKYLBENZYLAMINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-20 | — | — | US | disclosed |
| EP-3080070-A1 | METHOD FOR THE PREPARATION OF HALOGENATED DI-SUBSTITUTED BENZYLAMINES, IN PARTICULAR HALOGENATED DIALKYLBENZYLAMINES | Bayer CropScience Aktiengesellschaft (DE) | 2016-10-19 | — | — | EP | disclosed |
| CN-105814012-A | Method for the preparation of halogenated di-substituted benzylamines, in particular halogenated dialkylbenzylamines | 拜耳作物科学股份公司 | 2016-07-27 | — | — | CN | disclosed |
| WO-2015086490-A1 | METHOD FOR THE PREPARATION OF HALOGENATED DI-SUBSTITUTED BENZYLAMINES, IN PARTICULAR HALOGENATED DIALKYLBENZYLAMINES | BAYER CROPSCIENCE AG (DE) | 2015-06-18 | — | — | WO | disclosed |
| US-20100113778-A1 | PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2010-05-06 | — | — | US | disclosed |
| EP-2134673-A1 | IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008125592-A1 | IMPROVED PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113778-A1 | PROCESS FOR PREPARING O-CHLOROMETHYLPHENYLGLYOXYLIC ESTERS, IMPROVED PROCESS FOR PREPARING (E)-2-(2-CHLOROMETHYLPHENYL)-2-ALKOXIMINOACETIC ESTERS, AND NOVEL INTERMEDIATES FOR THEIR PREPARATION | CYP4F12, GRHPR, CYP4F2 | SLC6A2 3277/4885SLC6A4 1278/4885SLC6A3 4294/4885 |
| US-20160304435-A1 | PREPARATION OF HALOGENATED DI-SUBSTITUTED BENZYLAMINES, PARTICULARLY HALOGENATED DIALKYLBENZYLAMINES | DEK, DRD4, DCK | SLC6A2 624/4885SLC6A4 463/4885SLC6A3 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.