Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195320 | 0.76 | PLK1 (0.57) | PLK1AKR1C3AKR1C2AKR1C1HAO1 | |
| Methacrylic Acid SCHEMBL6914651 | 0.76 | — | — | |
| Diphenylsulfane SCHEMBL27974942 | 0.74 | HPGD (0.61) | AKR1C3MCL1ALDH1A1LMNAKDM4E | |
| SCHEMBL10110528 | 0.74 | PLK1 (0.55) | PLK1AKR1C3AKR1C2AKR1C1HAO1 | |
| SCHEMBL21715591 | 0.73 | PLK1 (0.48) | PLK1HAO1NOS3NOS1ALDH1A1 | |
| Methacrylic Acid SCHEMBL3426195 | 0.73 | TDP1 (0.47) | AKR1C3ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| Methacrylic Acid SCHEMBL225835 | 0.73 | TDP1 (0.47) | AKR1C3ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| Methacrylic Acid SCHEMBL3421717 | 0.73 | TDP1 (0.47) | AKR1C3ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| Methacrylic Acid SCHEMBL27638510 | 0.73 | — | — | |
| Methacrylic Acid SCHEMBL3858692 | 0.73 | TDP1 (0.47) | AKR1C3ALDH1A1LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345954-B1 | POLYROTAXANE, PRODUCTION METHOD THEREFOR, AND OPTICAL COMPOSITION CONTAINING SAID POLYROTAXANE | TOKUYAMA CORP (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-11578174-B2 | Polyrotaxane, production method therefor, and optical composition containing said polyrotaxane | TOKUYAMA CORPORATION (JP) | 2023-02-14 | — | — | US | disclosed |
| US-20220137261-A1 | OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2022-05-05 | — | — | US | disclosed |
| CN-112118955-B | Automatic injection method of mold for monomer for episulfide optical material | 可奥熙搜路司有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-112118955-A | Automatic injection method of mold for monomer for episulfide optical material | 可奥熙搜路司有限公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-2497791-B1 | METHOD FOR PRODUCING INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION INCLUDING THE SAME | MITSUI CHEMICALS INC (JP) | 2020-05-13 | — | — | EP | disclosed |
| US-20200071467-A1 | Polyrotaxane, Production Method Therefor, and Optical Composition Containing said Polyrotaxane | TOKUYAMA CORPORATION (JP) | 2020-03-05 | — | — | US | disclosed |
| EP-3150647-B1 | POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL AND METHOD FOR PRODUCING OPTICAL MATERIAL | MITSUI CHEMICALS INC (JP) | 2019-10-16 | — | — | EP | disclosed |
| US-RE47556-E1 | Optical element compound, optical material, and optical element | CANON KABUSHIKI KAISHA (JP) | 2019-08-06 | — | — | US | disclosed |
| EP-2390684-B1 | OPTICAL ELEMENT COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT | CANON KK (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-1058133-B1 | Polymerizable composition and process for producing optical resin comprising the same | MITSUI CHEMICALS INC (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6369269-B2 | Thiol and sulfur-containing O-(meth)acrylate compounds and use thereof | MITSUI CHEMICALS, INC. (JP) | 2002-04-09 | — | — | US | disclosed |
| US-6365707-B1 | CATALYTIC POLYEPOXIDES OR POLYTHIOEPOXIDES AND AMINO COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 2002-04-02 | — | — | US | disclosed |
| US-20010044555-A1 | Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof | KOBAYASHI SEIICHI (JP) | 2001-11-22 | — | — | US | disclosed |
| US-6265510-B1 | OPTICS; LENSES | MITSUI CHEMICALS, INC. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0810210-B1 | Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof | MITSUI CHEMICALS INC (JP) | 2001-01-10 | — | — | EP | disclosed |
| EP-1058133-A2 | Polymerizable composition and process for producing optical resin comprising the same | Mitsui Chemicals, Inc. (JP) | 2000-12-06 | — | — | EP | disclosed |
| US-6114485-A | STARTING MATERIAL FOR A RESIN COMPOSITION USED IN OPTICAL APPLICATIONS SUCH AS A LENS | MITSUI CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5916987-A | OPTICAL RESIN; LENSES | MITSUI CHEMICALS, INC. (JP) | 1999-06-29 | — | — | US | disclosed |
| EP-0810210-A2 | Thiol and sulfur-containing o-(meth)acrylate compounds and use thereof | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044555-A1 | Thiol and sulfur-containing O-(meth)acrylate counpounds and use thereof | MSRB3, BHMT2, HBS1L | PLK1 4318/4885AKR1C3 845/4885AKR1C2 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.