Sugi Predict

Sugi Predict / Compounds / SCHEMBL3314840

SCHEMBL3314840

SCHEMBL3314840

CNCCN1CCN(C(C)=O)CC1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CARM1 Q86X55 5/20 0.54
▸ PRMT6 Q96LA8 5/20 0.54
▸ PRMT8 Q9NR22 2/20 0.54
▸ PIK3CD O00329 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ PRMT1 Q99873 1/20 0.47
▸ CYP2C19 P33261 1/20 0.46
▸ SIGMAR1 Q99720 1/20 0.44
▸ DRD3 P35462 1/20 0.44
▸ HRH3 Q9Y5N1 1/20 0.43
▸ KDM1A O60341 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3319472 0.89 PIK3CD (0.47) CARM1PRMT6PRMT8PIK3CDCYP1A2
SCHEMBL39855 0.84 CARM1 (0.54) CARM1PRMT6PRMT8PRMT1CYP2C19
SCHEMBL23823660 0.83 CYP1A2 (0.64) PIK3CDCYP1A2TDP1SIGMAR1DRD3
SCHEMBL861660 0.82 CYP2C19 (0.53) PIK3CDCYP1A2TDP1CYP2C19SIGMAR1
SCHEMBL11501237 0.82 CARM1 (0.52) CARM1PRMT6PRMT8PRMT1CYP2C19
SCHEMBL3947861 0.81 PIK3CD (0.47) PIK3CDCYP1A2TDP1CYP2C19SIGMAR1
SCHEMBL12606943 0.80 CARM1 (0.54) CARM1PRMT6PRMT8PRMT1CYP2C19
SCHEMBL12510194 0.80 CARM1 (0.54) CARM1PRMT6PRMT8PRMT1
SCHEMBL1045046 0.80 CARM1 (0.79) CARM1PRMT6PRMT8PRMT1SIGMAR1
SCHEMBL240714 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100104659-A1 BENZOPYRANOPYRAZOLES 4SC AG (DE) 2010-04-29 — — US claimed
EP-2041141-A2 BENZOPYRANOPYRAZOLES 4SC AG (DE) 2009-04-01 — — EP claimed
WO-2008006883-A2 BENZOPYRANOPYRAZOLES 4SC AG (DE) 2008-01-17 — — WO claimed
US-11914248-B2 Photo-alignment copolymer, photo-alignment film, and optical laminate FUJIFILM CORPORATION (JP) 2024-02-27 — — US disclosed
EP-3640248-B1 AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) 2023-08-23 — — EP disclosed
US-20230213695-A1 LAMINATES, POLARIZING PLATES, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-20230217789-A1 OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-07-06 — — US disclosed
US-11635558-B2 Optical laminate and image display device FUJIFILM CORPORATION (JP) 2023-04-25 — — US disclosed
WO-2022255764-A1 NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE 주식회사 에즈큐리스 2022-12-08 — — WO disclosed
US-11352352-B2 Aminopyrimidine compound, preparation method therefor and use thereof Beijing Adamadle Biotechnology Limited Liability Company (CN) 2022-06-07 — — US disclosed
EP-3640248-A1 AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Beijing Adamadle Biotechnology Limited Liability Company (CN) 2020-04-22 — — EP disclosed
US-20110124641-A1 BENZOTHIAZOLE KINASE INHIBITORS AND METHODS OF USE INTELLIKINE LLC 2011-05-26 — — US disclosed
US-20110077268-A1 KINASE INHIBITORS AND METHODS OF USE INTELLIKINE LLC 2011-03-31 — — US disclosed
US-20100104659-A1 BENZOPYRANOPYRAZOLES 4SC AG (DE) 2010-04-29 — — US disclosed
WO-2009114870-A2 KINASE INHIBITORS AND METHODS OF USE INTELLIKINE, INC. (US) 2009-09-17 — — WO disclosed
WO-2009114874-A2 BENZOTHIAZOLE KINASE INHIBITORS AND METHODS OF USE INTELLIKINE, INC. (US) 2009-09-17 — — WO disclosed
EP-2041141-A2 BENZOPYRANOPYRAZOLES 4SC AG (DE) 2009-04-01 — — EP disclosed
WO-2008006883-A2 BENZOPYRANOPYRAZOLES 4SC AG (DE) 2008-01-17 — — WO disclosed
US-20070037739-A1 Compounds useful in coating stents to prevent and treat stenosis and restenosis MEDLOGICS DEVICE CORPORATION (US) 2007-02-15 — — US disclosed
US-20070037739-A1 Compounds useful in coating stents to prevent and treat stenosis and restenosis MEDLOGICS DEVICE CORPORATION (US) 2007-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077268-A1 KINASE INHIBITORS AND METHODS OF USE MAP3K20, MAP3K1, PDPK1 CARM1 1053/4885PRMT6 808/4885PRMT8 843/4885
US-20110124641-A1 BENZOTHIAZOLE KINASE INHIBITORS AND METHODS OF USE MTOR, PDPK1, PIKFYVE CARM1 1779/4885PRMT6 1421/4885PRMT8 1529/4885
US-20100104659-A1 BENZOPYRANOPYRAZOLES BAX, BCL2, BAD CARM1 1315/4885PRMT6 1631/4885PRMT8 2129/4885
US-11352352-B2 Aminopyrimidine compound, preparation method therefor and use thereof WEE1, WEE2, EGFR CARM1 3865/4885PRMT6 953/4885PRMT8 712/4885
US-20070037739-A1 Compounds useful in coating stents to prevent and treat stenosis and restenosis CAD, DBNL, DCAF15 CARM1 367/4885PRMT6 377/4885PRMT8 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.