Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 9/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 9/20 | 0.52 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39855 | 0.82 | CARM1 (0.54) | CARM1PRMT6PRMT8PRMT1CYP2C19 | |
| SCHEMBL3314840 | 0.82 | CARM1 (0.54) | CARM1PRMT6PRMT8PRMT1CYP2C19 | |
| SCHEMBL18850974 | 0.81 | NPSR1 (0.47) | CYP2C19SMN1; SMN2KMT2APOLB | |
| SCHEMBL30498993 | 0.81 | L3MBTL1 (0.57) | CARM1PRMT6PRMT8PRMT1SMN1; SMN2 | |
| SCHEMBL10316379 | 0.81 | CARM1 (0.52) | CARM1PRMT6PRMT8PRMT1ACE2 | |
| SCHEMBL1045046 | 0.78 | CARM1 (0.79) | CARM1PRMT6PRMT8PRMT1ACE2 | |
| SCHEMBL240714 | 0.78 | — | — | |
| SCHEMBL24127292 | 0.78 | CARM1 (0.48) | CARM1PRMT6PRMT8PRMT1CYP2C19 | |
| SCHEMBL16384393 | 0.78 | CYP2C19 (0.50) | CARM1PRMT6PRMT8PRMT1CYP2C19 | |
| SCHEMBL14000015 | 0.78 | CYP2C19 (0.43) | CYP2C19LTA4HSMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008696-A1 | Basically substituted urea compounds, process for producing the same and pharmaceutical compositions containing the same | Asta-Werke Aktiengesellschaft Chemische Fabrik (DE) | 1980-03-19 | — | — | EP | disclosed |