Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116712 | 0.93 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL6470818 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL10635279 | 0.91 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL8191123 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL9115758 | 0.89 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL6268919 | 0.87 | GAA (0.47) | ALDH1A1CYP3A4TDP1HTTL3MBTL1 | |
| Sulfuric Acid SCHEMBL8500882 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL3720237 | 0.85 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL8067053 | 0.83 | TLR8 (0.38) | ALDH1A1TDP1TSHRHTTL3MBTL1 | |
| SCHEMBL5495938 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1642117-B1 | REAGENT STRIPE FOR TEST STRIP | ROCHE DIABETES CARE GMBH (DE) | 2018-06-13 | — | — | EP | disclosed |
| EP-2972268-B1 | METHODS OF FAILSAFING ELECTROCHEMICAL MEASUREMENTS OF AN ANALYTE AS WELL AS DEVICES, APPARATUSES AND SYSTEMS INCORPORATING THE SAME | ROCHE DIABETES CARE GMBH (DE) | 2017-05-24 | — | — | EP | disclosed |
| US-8211379-B2 | Test strip with slot vent opening | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-07-03 | — | — | US | disclosed |
| US-8142721-B2 | Test strip with slot vent opening | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-27 | — | — | US | disclosed |
| US-8119414-B2 | Test strip with slot vent opening | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20120009095-A1 | TEST STRIP WITH SLOT VENT OPENING | ROCHE DIABETES CARE, INC. | 2012-01-12 | — | — | US | disclosed |
| US-8071030-B2 | Wider opening provided by invention is easier to \"target\" with a sample fluid; aids user in introducing sample to test device, and reduces dose hesitation | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071030-B2 | Wider opening provided by invention is easier to \"target\" with a sample fluid; aids user in introducing sample to test device, and reduces dose hesitation | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-7892849-B2 | Reagent stripe for test strip | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7892849-B2 | Reagent stripe for test strip | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20110000610-A1 | TEST STRIP WITH SLOT VENT OPENING | ROCHE DIABETES CARE, INC. | 2011-01-06 | — | — | US | disclosed |
| US-7829023-B2 | Easy dosing; robust, flexible; allows air to escape as fluid enters sampling chamber; accurate, fast; reduced sample size; blood glucose monitoring | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829023-B2 | Easy dosing; robust, flexible; allows air to escape as fluid enters sampling chamber; accurate, fast; reduced sample size; blood glucose monitoring | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7727467-B2 | Reagent stripe for test strip | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-7727467-B2 | Reagent stripe for test strip | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | disclosed |
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | disclosed |
| US-20100105655-A1 | NOVEL COMPOUNDS 515 | ASTRAZENECA AB | 2010-04-29 | — | — | US | disclosed |
| US-20090151864-A1 | REAGENT STRIPE FOR TEST STRIP | ROCHE DIABETES CARE, INC. | 2009-06-18 | — | — | US | disclosed |
| US-20090151864-A1 | REAGENT STRIPE FOR TEST STRIP | ROCHE DIABETES CARE, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105655-A1 | NOVEL COMPOUNDS 515 | TYMS, ABCG2, UMPS | ALDH1A1 649/4885CYP3A4 49/4885TDP1 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.