Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316307 | 1.00 | MAPT (0.45) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3312529 | 1.00 | MAPT (0.45) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3316494 | 0.89 | KDM4E (0.41) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5968378 | 0.83 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10684176 | 0.80 | KAT8 (0.51) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7107682 | 0.80 | KAT8 (0.51) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11221674 | 0.80 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28835732 | 0.80 | TLR8 (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10970707 | 0.79 | KDM4E (0.49) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7731575 | 0.79 | POLB (0.49) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015586-A2 | 2,3,4,7-TETRAHYDRO-INDOLO[2,3-C]QUINOLINE COMPOUNDS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |