Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689889 | 0.95 | HPGD (0.50) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10976271 | 0.95 | HPGD (0.50) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10933274 | 0.89 | ALOX5 (0.49) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11225617 | 0.88 | TRPM4 (0.48) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL299862 | 0.84 | MAPT (0.53) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6545326 | 0.83 | HPGD (0.47) | HPGDKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL11024895 | 0.83 | NCEH1 (0.45) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16267503 | 0.82 | MAPT (0.55) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16267023 | 0.82 | MAPT (0.55) | MAPTHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5116260 | 0.82 | MAPT (0.55) | MAPTHPGDKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323714-A | Alkylation of hydroxy-substituted aromatic compounds | UOP INC. (US) | 1982-04-06 | — | — | US | disclosed |