Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 11/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207997 | 0.81 | LSS (0.39) | ALDH1A1LSSMEN1KMT2A | |
| SCHEMBL10256965 | 0.79 | KMT2A (0.48) | ALDH1A1LTA4HMEN1KMT2AFAAH | |
| Hydrochloric Acid SCHEMBL27738298 | 0.79 | MEN1 (0.42) | ALDH1A1LSSMEN1KMT2A | |
| SCHEMBL9663210 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2A | |
| Acrylamide SCHEMBL28130764 | 0.76 | ALDH1A1 (0.42) | ALDH1A1LSSPYCR1 | |
| Acrylamide SCHEMBL28273458 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LSSPYCR1 | |
| SCHEMBL5618693 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| Acrylamide SCHEMBL28075507 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LSSPYCR1 | |
| SCHEMBL27095807 | 0.74 | PYCR1 (0.41) | LSSPYCR1 | |
| SCHEMBL7866824 | 0.73 | ABCC4 (0.45) | ALDH1A1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | ALDH1A1 474/4885LSS 1914/4885LTA4H 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.