⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10540085 | 0.90 | PRMT3 (0.43) | — | |
| SCHEMBL3317561 | 0.87 | PRMT3 (0.42) | — | |
| SCHEMBL1697723 | 0.86 | PRMT1 (0.65) | — | |
| SCHEMBL12571527 | 0.85 | PRMT3 (0.46) | — | |
| SCHEMBL26495264 | 0.83 | PRMT3 (0.39) | — | |
| SCHEMBL26495198 | 0.83 | PRMT3 (0.44) | — | |
| SCHEMBL4083018 | 0.83 | PRMT3 (0.44) | — | |
| SCHEMBL7179758 | 0.83 | PRMT1 (0.61) | — | |
| Dimethylamine SCHEMBL3990355 | 0.83 | MAPT (0.50) | — | |
| SCHEMBL26494037 | 0.81 | S1PR2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115386271-A | Antibacterial and mildewproof aluminum profile powder coating and preparation method thereof | 安徽登王化工有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-108976789-A | A kind of enhanced heat-resistant cable filler composition | 安徽省通信产业服务有限公司 | 2018-12-11 | — | — | CN | claimed |
| WO-1995003874-A1 | SOLVENT COMPOSITION FOR REMOVING ACID GASES | THE DOW CHEMICAL COMPANY (US) | 1995-02-09 | — | — | WO | claimed |
| US-5246619-A | Condensation of monoethanolamine, n-methyl- | THE DOW CHEMICAL COMPANY (US) | 1993-09-21 | — | — | US | claimed |
| WO-2024015055-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-6-YL-SULFONAMIDE DERIVATIVES FOR THE INHIBITION OF SGK-1 AND TREATMENT OF CANCER | THRYV THERAPEUTICS INC. (CA) | 2024-01-18 | — | — | WO | disclosed |
| WO-2024011307-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-6-YL-SULFONAMIDE DERIVATIVES FOR THE INHIBITION OF SGK-1 AND TREATMENT OF CANCER | THRYV THERAPEUTICS INC. (CA) | 2024-01-18 | — | — | WO | disclosed |
| EP-4277905-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-6-YL-SULFONAMIDE DERIVATIVES FOR THE INHIBITION OF SGK-1 | THRYV Therapeutics Inc. (CA) | 2023-11-22 | — | — | EP | disclosed |
| CN-117062817-A | Pyrazolo [3,4-D ] pyrimidin-6-yl-sulfonamide derivatives for SGK-1 inhibition | 斯瑞福治疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2023196444-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| CN-115476411-B | Method for producing aldehyde-free plywood | 万华化学集团股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2023141426-A1 | ALKANOLAMINE-CONTAINING MEMBRANES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-07-27 | — | — | WO | disclosed |
| US-20090048223-A1 | Sulfonamide compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| WO-2008006883-A2 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| US-20070149538-A1 | Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors | IRM LLC (BM) | 2007-06-28 | — | — | US | disclosed |
| US-7183325-B2 | Deforming agent and/or deaerating agent based on oil-in-water dispersions | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-27 | — | — | US | disclosed |
| US-5491263-A | DECYCLIZATION OF AN OXAZOLIDINONE WITH A SECONDARY AMINE OR A SECONDARY ALKANOLAMINE | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5246619-A | Condensation of monoethanolamine, n-methyl- | THE DOW CHEMICAL COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0135909-B1 | CATHODICALLY DEPOSITABLE AQUEOUS ELECTRODIPPING COATING COMPOSITION | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1987-08-12 | — | — | EP | disclosed |
| US-4623690-A | Cathodically precipitable aqueous electro-dipcoating agent | HERBERTS GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1986-11-18 | — | — | US | disclosed |