Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940846 | 0.86 | MAPT (0.39) | CYP2C9CYP2C19TDP1MAPT | |
| SCHEMBL3316611 | 0.83 | — | — | |
| SCHEMBL15189352 | 0.83 | PRMT1 (0.50) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL25792055 | 0.82 | CYP2C9 (0.33) | CYP2C9CYP2C19TDP1MAPT | |
| SCHEMBL8503680 | 0.81 | PRMT1 (0.70) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Diethanolamine SCHEMBL27473413 | 0.80 | MAPT (0.43) | CYP2C9CYP2C19TDP1MAPT | |
| SCHEMBL1697723 | 0.80 | PRMT1 (0.65) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL2750873 | 0.79 | PRMT3 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL13752280 | 0.79 | CYP2C9 (0.34) | CYP2C9CYP2C19TDP1MAPT | |
| SCHEMBL12571527 | 0.79 | PRMT3 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035464-A1 | 1,2-DITHIOL-3-THIONES AS CHAIN-TRANSFER AGENTS IN FREE-RADICAL POLYMERIZATION REACTIONS | BASF SE (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007147857-A1 | 1,2-DITHIOL-3-THIONES AS CHAIN-TRANSFER AGENTS IN FREE-RADICAL POLYMERIZATION REACTIONS | BASF SE (DE) | 2007-12-27 | — | — | WO | disclosed |