Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613922 | 0.86 | GAA (0.47) | PDE2AALDH1A1CASREPHX2EPHX1 | |
| SCHEMBL3314353 | 0.81 | KDM1A (0.51) | ALDH1A1SLC6A4GAAL3MBTL1 | |
| SCHEMBL3314991 | 0.78 | ADRB2 (0.54) | ALDH1A1SLC6A4SLC6A3GAAL3MBTL1 | |
| SCHEMBL3316343 | 0.78 | GAA (0.49) | SLC6A4SLC6A3GAAL3MBTL1 | |
| SCHEMBL3317082 | 0.77 | EPHX2 (0.45) | PDE2AALDH1A1EPHX2EPHX1 | |
| SCHEMBL22424343 | 0.74 | PDE2A (0.51) | PDE2AALDH1A1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL10087242 | 0.74 | PDE2A (0.51) | PDE2AALDH1A1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL765243 | 0.74 | PDE2A (0.51) | PDE2AALDH1A1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL18476237 | 0.74 | PDE2A (0.51) | PDE2AALDH1A1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL28869406 | 0.74 | PDE2A (0.51) | PDE2AALDH1A1ATP1A1ATP1B1ATP1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105681-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | LASSOIE MARIE-AGNES | 2010-04-29 | — | — | US | disclosed |
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | VERNALIS (R&D) LIMITED (GB) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | CNR1, OPRL1, CHRNA10 | PDE2A 1665/4885ALDH1A1 1255/4885CASR 117/4885 |
| US-20100105681-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | SCN4A, NECTIN4, VPS4B | PDE2A 1998/4885ALDH1A1 1048/4885CASR 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.