Thioglycolic Acid

Thioglycolic Acid

SCHEMBL331732

O=C(O)CS.O=C(O)CS.SCCOCCS

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.38
HSD17B10 Q99714 2/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
ACE P12821 1/20 0.36
TSHR P16473 1/20 0.33
ANPEP P15144 1/20 0.31
ENPEP Q07075 1/20 0.31
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL28085270 1.00 FOLH1 (0.38) FOLH1HSD17B10BLMPMP22ACE
Mercaptopropionic Acid SCHEMBL331255 0.83 ACE (0.50) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL6366305 0.83
Acetic Acid SCHEMBL28323745 0.82 FFAR3 (0.41) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL30505307 0.81 FOLH1 (0.44) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL7943429 0.81 HSD17B10 (0.38) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL39838 0.81 FOLH1 (0.44) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL12092215 0.81 FOLH1 (0.44) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL13907082 0.81 FOLH1 (0.44) FOLH1HSD17B10BLMPMP22ACE
SCHEMBL40095 0.81 FOLH1 (0.44) FOLH1HSD17B10BLMPMP22ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 565 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US claimed
CN-118745246-A High refractive material based on biomass magnolol and honokiol 中国科学院上海有机化学研究所 2024-10-08 CN claimed
CN-111748069-B Optical resin composition and optical resin material prepared from same 万华化学集团股份有限公司 2022-04-22 CN claimed
CN-111333803-B Optical resin composition, optical resin material and application thereof 万华化学集团股份有限公司 2022-02-18 CN claimed
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
US-6391433-B1 None US disclosed
CN-121574342-A Benzenedimethylene diisocyanate composition, preparation method and application thereof 万华化学集团股份有限公司 2026-02-27 CN disclosed
EP-4674881-A2 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, RESIN, MOLDED BODY, OPTICAL ELEMENT AND LENS Mitsui Chemicals, Inc. (JP) 2026-01-07 EP disclosed
EP-3919584-B1 METHOD FOR PRODUCING POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2025-12-24 EP disclosed
EP-4151623-B1 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, RESIN, MOLDED BODY, OPTICAL ELEMENT AND LENS MITSUI CHEMICALS INC (JP) 2025-11-26 EP disclosed
US-12441821-B2 (Meth)acrylate and use thereof MITSUI CHEMICALS, INC. (JP) 2025-10-14 US disclosed
EP-4620947-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL Wanhua Chemical Group Co., Ltd. (CN) 2025-09-24 EP disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed
EP-0374258-A1 HIGH REFRACTIVE INDEX LENS AND METHOD FOR ITS PRODUCTION MITSUI CHEMICALS, INC. (JP) 1990-06-27 EP disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441821-B2 (Meth)acrylate and use thereof TST, MMAB, BHMT2 FOLH1 4307/4885HSD17B10 1153/4885BLM 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.