Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842526 | 0.90 | ATM (0.31) | ATMLPAR5 | |
| SCHEMBL331749 | 0.90 | ATM (0.31) | ATMLPAR5 | |
| SCHEMBL12094888 | 0.87 | LPAR5 (0.31) | LPAR5 | |
| SCHEMBL410909 | 0.86 | TSHR (0.41) | LPAR5 | |
| SCHEMBL22712844 | 0.85 | ATM (0.37) | ATMLPAR5 | |
| SCHEMBL1718931 | 0.83 | ATM (0.44) | ATM | |
| SCHEMBL1046295 | 0.83 | LPAR5 (0.41) | ATMLPAR5 | |
| SCHEMBL996290 | 0.83 | LPAR5 (0.37) | ATMLPAR5 | |
| SCHEMBL22319047 | 0.82 | ALDH1A1 (0.36) | ATM | |
| SCHEMBL35419 | 0.82 | USP2 (0.34) | LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3598181-B1 | VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME | ALCON INC (CH) | 2021-06-23 | — | — | EP | claimed |
| EP-2281583-B1 | Contact lens packages containing additives | JOHNSON & JOHNSON VISION CARE (US) | 2015-07-08 | — | — | EP | claimed |
| US-8404759-B2 | soft contact lens has a hydrophilic surface without post-curing surface treatment; macromolecular monomer of oligosiloxane mono-endcapped with (meth)acrylate or (meth)acrylamide, that copolymerizes with hydrophilic monomer and a vinylic ketone monomer | NOVARTIS AG (CH) | 2013-03-26 | — | — | US | claimed |
| EP-1704875-B1 | Contact lens packages containing additives | JOHNSON & JOHNSON VISION CARE (US) | 2013-03-13 | — | — | EP | claimed |
| EP-2356497-A2 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS | Novartis AG (CH) | 2011-08-17 | — | — | EP | claimed |
| WO-2010056687-A2 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS | NOVARTIS AG (CH) | 2010-05-20 | — | — | WO | claimed |
| US-12054590-B2 | Hydrogel polymers | GL CHEMTEC VISION INC. (CA) | 2024-08-06 | — | — | US | disclosed |
| EP-4360861-A2 | PROCESS OF MAKING AN OPHTALMICAL DEVICE FOR THE SUPPLY OF HYDROPHOBIC COMFORT AGENTS | Alcon Inc. (CH) | 2024-05-01 | — | — | EP | disclosed |
| EP-3373047-B1 | PROCESS OF MAKING AN OPHTALMICAL DEVICE FOR THE SUPPLY OF HYDROPHOBIC COMFORT AGENTS | ALCON INC (CH) | 2024-03-06 | — | — | EP | disclosed |
| US-11873280-B2 | Cross-linking agent(s) | GL CHEMTEC VISION INC. (CA) | 2024-01-16 | — | — | US | disclosed |
| US-20210340336-A1 | HYDROGEL POLYMERS | GL CHEMTEC VISION INC. (CA) | 2021-11-04 | — | — | US | disclosed |
| EP-3598181-B1 | VINYLIC MONOMER AND PREPOLYMER COMPRISING SAME | ALCON INC (CH) | 2021-06-23 | — | — | EP | disclosed |
| US-20210129467-A1 | OPHTHALMIC DEVICES FOR DELIVERY OF HYDROPHOBIC COMFORT AGENTS | NOVARTIS AG (CH) | 2021-05-06 | — | — | US | disclosed |
| WO-2011037897-A2 | MATERIALS FOR USE IN OPHTHALMIC APPLICATIONS AND METHODS | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2011-03-31 | — | — | WO | disclosed |
| EP-2262631-A1 | METHOD FOR CAST MOLDING CONTACT LENSES | Novartis AG (CH) | 2010-12-22 | — | — | EP | disclosed |
| WO-2010065686-A1 | OPHTHALMIC DEVICES FOR DELIVERY OF HYDROPHOBIC COMFORT AGENTS | NOVARTIS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| WO-2010056687-A2 | SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS | NOVARTIS AG (CH) | 2010-05-20 | — | — | WO | disclosed |
| EP-2129513-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | Novartis Ag (CH) | 2009-12-09 | — | — | EP | disclosed |
| WO-2009114490-A1 | METHOD FOR CAST MOLDING CONTACT LENSES | NOVARTIS AG (CH) | 2009-09-17 | — | — | WO | disclosed |
| WO-2008116131-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873280-B2 | Cross-linking agent(s) | WASF2, ITK, MACF1 | ATM 954/4885LPAR5 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.