Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18399534 | 0.79 | TRPM8 (0.33) | TRPM8 | |
| SCHEMBL575153 | 0.72 | TRPM8 (0.36) | TRPM8 | |
| SCHEMBL5484409 | 0.70 | TRPM8 (0.34) | TRPM8 | |
| SCHEMBL26205828 | 0.69 | NPSR1 (0.34) | TRPM8 | |
| SCHEMBL21264893 | 0.69 | TRPM8 (0.40) | TRPM8 | |
| SCHEMBL575511 | 0.68 | TSHR (0.46) | TRPM8 | |
| SCHEMBL28665435 | 0.68 | — | — | |
| SCHEMBL585621 | 0.68 | ALDH1A1 (0.35) | TRPM8 | |
| SCHEMBL28660557 | 0.67 | ANPEP (0.35) | — | |
| SCHEMBL5494693 | 0.67 | CYP3A4 (0.37) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756126-B1 | PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS | ICL IP AMERICA INC (US) | 2012-02-08 | — | — | EP | claimed |
| US-8097747-B2 | Process for the alkylation of phosphorus-containing compounds | ICL-IP America Inc (US) | 2012-01-17 | — | — | US | claimed |
| US-20090054675-A1 | Process for the alkylation of phosphorus-containing compounds | SUPRESTA LLCC (US) | 2009-02-26 | — | — | US | claimed |
| JP-2007534685-A | — | — | 2007-11-29 | — | — | JP | claimed |
| EP-1756126-A1 | PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS | Supresta LLC (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005105818-A1 | PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS | SUPRESTA LLC (US) | 2005-11-10 | — | — | WO | claimed |
| EP-1756126-B1 | PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS | ICL IP AMERICA INC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-8097747-B2 | Process for the alkylation of phosphorus-containing compounds | ICL-IP America Inc (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090054675-A1 | Process for the alkylation of phosphorus-containing compounds | SUPRESTA LLCC (US) | 2009-02-26 | — | — | US | disclosed |
| EP-1756126-A1 | PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS | Supresta LLC (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005105818-A1 | PROCESS FOR THE ALKYLATION OF PHOSPHORUS-CONTAINING COMPOUNDS | SUPRESTA LLC (US) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054675-A1 | Process for the alkylation of phosphorus-containing compounds | PHOSPHO1, INPP5D, INPPL1 | TRPM8 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.