Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272031 | 0.78 | KDM4E (0.40) | SMN1; SMN2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL244861 | 0.76 | PSIP1 (0.32) | — | |
| SCHEMBL244860 | 0.76 | PSIP1 (0.32) | — | |
| SCHEMBL18891845 | 0.70 | CSF1R (0.37) | SMN1; SMN2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL20020922 | 0.65 | EZH2 (0.41) | SMN1; SMN2KDM4EMAPTKMT2ALMNA | |
| SCHEMBL3297610 | 0.62 | KDM4E (0.54) | SMN1; SMN2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3303954 | 0.61 | KDM4E (0.53) | SMN1; SMN2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3303958 | 0.61 | KMT2A (0.49) | SMN1; SMN2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL20020884 | 0.61 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL20020731 | 0.61 | KDM4E (0.49) | SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003498-A1 | 2 -QUINOLINYL- ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |