SCHEMBL3318629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3318665	0.90	NPC1 (0.38)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL13397746	0.90	NPC1 (0.38)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL3316283	0.90	ALDH1A1 (0.37)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL3321538	0.90	ALDH1A1 (0.37)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL3318341	0.86	POLB (0.40)	ALDH1A1NPC1RAB9ALMNASMN1; SMN2
	SCHEMBL3316688	0.86	NPC1 (0.35)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL3319630	0.86	ALDH1A1 (0.34)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL3317309	0.86	ALDH1A1 (0.34)	HTTALDH1A1NPC1RAB9AKDM2B
	SCHEMBL3316425	0.85	KDM4E (0.46)	ALDH1A1NPC1RAB9AL3MBTL1POLB
	SCHEMBL3318434	0.84	SMN1; SMN2 (0.47)	ALDH1A1NPC1RAB9AL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.