SCHEMBL3318341

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3318434	0.90	SMN1; SMN2 (0.47)	POLBALDH1A1LMNAGAASMN1; SMN2
	SCHEMBL3314637	0.90	SMN1; SMN2 (0.45)	POLBALDH1A1GAAOPRM1SMN1; SMN2
	SCHEMBL3314415	0.90	ALDH1A1 (0.40)	ALDH1A1OPRM1SMN1; SMN2CYP1A2CYP2C19
	SCHEMBL3318083	0.89	FKBP1A (0.37)	SMN1; SMN2NPC1CYP1A2HPGDCYP2C19
	SCHEMBL13398010	0.89	FKBP1A (0.37)	SMN1; SMN2NPC1CYP1A2HPGDCYP2C19
	SCHEMBL3321277	0.88	KMT2A (0.42)	POLBALDH1A1LMNAGAASMN1; SMN2
	SCHEMBL3318629	0.86	HTT (0.39)	POLBALDH1A1LMNAGAASMN1; SMN2
	SCHEMBL3320782	0.85	LMNA (0.41)	POLBALDH1A1LMNASMN1; SMN2NPC1
	SCHEMBL3314062	0.85	FKBP1A (0.35)	SMN1; SMN2NPC1CYP1A2HPGDCYP2C19
	SCHEMBL3316425	0.83	KDM4E (0.46)	POLBALDH1A1NPC1CYP2C19RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.