⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452627 | 0.71 | CDK2 (0.32) | — | |
| SCHEMBL6322394 | 0.61 | DCPS (0.30) | — | |
| SCHEMBL1025894 | 0.59 | CCNA2 (0.37) | — | |
| SCHEMBL1627470 | 0.54 | PI4KA (0.31) | — | |
| SCHEMBL2411626 | 0.54 | — | — | |
| SCHEMBL6741526 | 0.52 | NOS2 (0.37) | — | |
| SCHEMBL22207103 | 0.51 | — | — | |
| SCHEMBL1417542 | 0.51 | — | — | |
| SCHEMBL13969366 | 0.47 | — | — | |
| SCHEMBL17299130 | 0.47 | NQO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814504-A1 | APTAMERS FOR PERSONAL CARE APPLICATIONS | The Procter & Gamble Company (US) | 2021-05-05 | — | — | EP | claimed |
| US-8324179-B2 | Nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-20100104532-A1 | NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| WO-2008100447-A2 | NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2008-08-21 | — | — | WO | disclosed |
| WO-2006091905-A1 | BICYCLO (3.1.0) HEXANE DERIVATIVES AS ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-08-31 | — | — | WO | disclosed |