SCHEMBL3318941

SCHEMBL3318941

CC(C)(O)[SiH2]c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
ALOX15 P16050 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 5/20 0.33
KMT2A Q03164 2/20 0.33
MAPK1 P28482 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 3/20 0.32
PDK1 Q15118 2/20 0.31
PDK2 Q15119 2/20 0.31
PDK3 Q15120 2/20 0.31
PDK4 Q16654 2/20 0.31
HDAC3 O15379 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27586356 0.86 MEN1 (0.31) KMT2AMEN1
SCHEMBL1254751 0.78 MAPK1 (0.36) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL28738479 0.78 CA12 (0.33) ALDH1A1MAPTCYP2C19TDP1CA12
SCHEMBL27586360 0.76 ALDH1A1 (0.33) ALDH1A1ALOX15ESR1ESR2CYP3A4
Ethane SCHEMBL8430515 0.76 MAPK1 (0.35) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL5364566 0.74 TAAR1 (0.41) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL7033571 0.74 MAPK1 (0.33) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL27841371 0.72 CYP1A2 (0.38) ALDH1A1ALOX15ESR1ESR2CYP3A4
SCHEMBL11206931 0.70 MAPT (0.36) ALDH1A1ALOX15CYP3A4TSHRKMT2A
SCHEMBL3063901 0.70 MAPK1 (0.36) ALDH1A1ALOX15MAPK1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61263988-A None JP disclosed
US-8460069-B2 Lens holder HOYA CORPORATION (JP) 2013-06-11 US disclosed
US-8216024-B2 Spectacle lens edging method HOYA CORPORATION (JP) 2012-07-10 US disclosed
EP-2140971-B1 LENS HOLDER HOYA CORP (JP) 2012-05-23 EP disclosed
US-20100112915-A1 LENS HOLDER HOYA CORPORATION (JP) 2010-05-06 US disclosed
US-20100105293-A1 SPECTACLE LENS EDGING METHOD HOYA CORPORATION (JP) 2010-04-29 US disclosed
EP-2140971-A1 LENS HOLDER Hoya Corporation (JP) 2010-01-06 EP disclosed
EP-2138269-A1 METHOD FOR EDGING LENS OF GLASSES Hoya Corporation (JP) 2009-12-30 EP disclosed
US-7318959-B2 Optical element having antireflection film HOYA CORPORATION (JP) 2008-01-15 US disclosed
EP-1433809-B1 Optical member having antireflection film HOYA CORP (JP) 2006-09-20 EP disclosed
EP-1433809-A1 Optical member having antireflection film HOYA CORPORATION (JP) 2004-06-30 EP disclosed
US-20010005738-A1 Building blocks containing isocyanate groups and their use for functionalizing or modifying compounds or surfaces BASF AKTIENGESELLSCHAFT (DE) 2001-06-28 US disclosed
EP-1110946-A2 Subunits containing isocyanate groups and their use for functionalising or modifying compounds or surfaces BASF AKTIENGESELLSCHAFT (DE) 2001-06-27 EP disclosed
US-6232261-B1 REACTION PRODUCT OF AN ALUMINOXANE OR PRODUCT OF AN ALKYLALUMINUM AND WATER WITH A SILICON-CONTAINING COMPOUND, FOR EXAMPLE DIPHENYLSILANE DIOL; OLEFIN POLYMERIZATION CATALYST, ESPECIALLY A METALLOCENE COMPLEX BP CHEMICALS LIMITED (GB) 2001-05-15 US disclosed
EP-0952991-A1 CATALYST ACTIVATORS BP Chemicals Limited (GB) 1999-11-03 EP disclosed
WO-1998031715-A1 CATALYST ACTIVATORS BP CHEMICALS LIMITED (GB) 1998-07-23 WO disclosed
EP-0202893-B1 PESTICIDAL SILYLMETHYL ETHER COMPOUNDS SHIONOGI & CO., LTD. (JP) 1990-01-03 EP disclosed
US-4663314-A PESTICIDES SHIONOGI & CO., LTD. (JP) 1987-05-05 US disclosed
EP-0202893-A2 Pesticidal silylmethyl ether compounds SHIONOGI & CO., LTD. (JP) 1986-11-26 EP disclosed
JP-S61263988-A SILYL-SUBSTITUTED ETHER AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME SHIONOGI & CO LTD 1986-11-21 JP disclosed